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Filip K. Knop
Researcher at University of Copenhagen
Publications - 523
Citations - 17834
Filip K. Knop is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 61, co-authored 437 publications receiving 13614 citations. Previous affiliations of Filip K. Knop include Copenhagen University Hospital & Victor Chang Cardiac Research Institute.
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Journal ArticleDOI
Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials
TL;DR: Evidence is provided that treatment with GLP-1R agonists leads to weight loss in overweight or obese patients with or without type 2 diabetes mellitus.
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Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition
Ruud S. Kootte,Evgeni Levin,Jarkko Salojärvi,Loek P. Smits,Annick V. Hartstra,Shanti D. Udayappan,Gerben D. A. Hermes,Kristien E. C. Bouter,Annefleur M. Koopen,Jens J. Holst,Filip K. Knop,Ellen E. Blaak,Jing Hua Zhao,Hauke Smidt,Amy C. Harms,Thomas Hankemeijer,Jacques J. Bergman,Hans A. Romijn,Frank G. Schaap,Steven W.M. Olde Damink,Mariëtte T. Ackermans,Geesje M. Dallinga-Thie,Erwin G. Zoetendal,Willem M. de Vos,Mireille J. Serlie,Erik S.G. Stroes,Albert K. Groen,Max Nieuwdorp +27 more
TL;DR: The beneficial effects of lean donor FMT on glucose metabolism are associated with changes in intestinal microbiota and plasma metabolites and can be predicted based on baseline fecal microbiota composition.
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Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity
A. Vrieze,Carolien Out,Susana Fuentes,Lisanne Jonker,Isaie J. Reuling,Ruud S. Kootte,Els van Nood,Frits Holleman,Max Knaapen,Johannes A. Romijn,Maarten R. Soeters,Ellen E. Blaak,Geesje M. Dallinga-Thie,Dorien Reijnders,Mariëtte T. Ackermans,Mireille J. Serlie,Filip K. Knop,Filip K. Knop,Jenst J. Holst,Claude van der Ley,Ido P. Kema,Erwin G. Zoetendal,Willem M. de Vos,Willem M. de Vos,Joost B. L. Hoekstra,Erik S.G. Stroes,Albert K. Groen,Max Nieuwdorp +27 more
TL;DR: Oral administration of vancomycin significantly impacts host physiology by decreasing intestinal microbiota diversity, bile acid dehydroxylation and peripheral insulin sensitivity in subjects with metabolic syndrome.
Journal ArticleDOI
Recovery of gut microbiota of healthy adults following antibiotic exposure
Albert Pallejà,Kristian Hallundbæk Mikkelsen,Sofia K. Forslund,Alireza Kashani,Kristine H. Allin,Kristine H. Allin,Trine Nielsen,Tue H. Hansen,Suisha Liang,Qiang Feng,Chenchen Zhang,Paul Theodor Pyl,Luis Pedro Coelho,Huanming Yang,Jian Wang,Athanasios Typas,Morten Frost Munk Nielsen,Henrik Nielsen,Peer Bork,Jun Wang,Tina Vilsbøll,Torben Hansen,Torben Hansen,Filip K. Knop,Manimozhiyan Arumugam,Oluf Pedersen +25 more
TL;DR: It is shown that the human gut microbiome can recover after a clinically relevant, broad-spectrum antibiotic treatment and characterization of the resistome indicates that antibiotic resistance genes can impact the recovery process.
Journal ArticleDOI
Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?
Filip K. Knop,Tina Vilsbøll,Patricia V. Højberg,Steen Larsen,Sten Madsbad,Aage Vølund,Jens J. Holst,Thure Krarup +7 more
TL;DR: The results suggest that the reduced incretin effect is not a primary event in the development of type 2 diabetes, but rather a consequence of the diabetic state.