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Gary C. Brown
Researcher at Thomas Jefferson University
Publications - 264
Citations - 9480
Gary C. Brown is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Macular degeneration & Visual acuity. The author has an hindex of 53, co-authored 262 publications receiving 8909 citations.
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Journal ArticleDOI
Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration
Wei Chen,Dwight Stambolian,Albert O. Edwards,Kari Branham,Mohammad Othman,Johanna Jakobsdottir,Nirubol Tosakulwong,Margaret A. Pericak-Vance,Peter A. Campochiaro,Michael L. Klein,Perciliz L. Tan,Yvette P. Conley,Atsuhiro Kanda,Laura J. Kopplin,Yanming Li,Katherine J. Augustaitis,Athanasios J. Karoukis,William K. Scott,Anita Agarwal,Jaclyn L. Kovach,Stephen G. Schwartz,Eric A. Postel,Matthew Brooks,Keith H. Baratz,William L. Brown,Alexander J. Brucker,Anton Orlin,Gary C. Brown,Allen C. Ho,Carl D. Regillo,Larry A. Donoso,Lifeng Tian,Brian Kaderli,Dexter Hadley,Stephanie A. Hagstrom,Stephanie A. Hagstrom,Neal S. Peachey,Neal S. Peachey,Neal S. Peachey,Ronald Klein,Barbara E.K. Klein,Norimoto Gotoh,Kenji Yamashiro,Frederick L. Ferris,Jesen Fagerness,Robyn Reynolds,Lindsay A. Farrer,Ivana K. Kim,Joan W. Miller,Marta Corton,Angel Carracedo,Manuel Sánchez-Salorio,Elizabeth W. Pugh,Kimberly F. Doheny,Maria Brion,Margaret M. DeAngelis,Daniel E. Weeks,Donald J. Zack,Emily Y. Chew,John R. Heckenlively,Nagahisa Yoshimura,Sudha K. Iyengar,Peter J. Francis,Nicholas Katsanis,Johanna M. Seddon,Jonathan L. Haines,Michael B. Gorin,Gonçalo R. Abecasis,Anand Swaroop,Anand Swaroop +69 more
TL;DR: A genome-wide association scan for age-related macular degeneration (AMD) showed that 329 of 331 individuals with the highest-risk genotypes were cases, and 85% of these had advanced AMD, consistent with the hypothesis that HDL metabolism is associated with AMD pathogenesis.
Journal ArticleDOI
Aspirin Effects on Mortality and Morbidity in Patients With Diabetes Mellitus: Early Treatment Diabetic Retinopathy Study Report 14
Aaron Kassoff,Sheldon M. Buzney,J. Wallace McMeel,John J. Weiter,Gerald J. Doyle,Rodney L. Immerman,Gerald R. Friedman,Michael L. Klein,Richard F. Dreyer,Richard Chenoweth,Irvin Handelman,Richard Hohl,Robert Biesbroeck,Jack O. Sipperley,Charles A. Garcia,Michael A. Bloome,Richard S. Ruiz,F. Tempel Riekhof,William A. Bohart,Roy A. Goodart,Dana H. Clarke,David H. Orth,Timothy P. Flood,Kirk H. Packo,Jayant Malhotra,Akbar Rahmani,Edward J. Winter,Harish Bhatia,Robert P. Murphy,Stuart L. Fine,Michael J. Elman,Frederick L. Ferris,Thaddeus E. Prout,Arnall Patz,Thomas A. Rice,David Newsome,Lloyd M. Aiello,Lawrence I. Rand,S. Shah,Ramachandiran Cooppan,Jerry Cavallerano,Robert L. Poole,Philip Silver,Jose Briones,Mohammed Z. Wafai,Abdul C. Asmal,Rudolph M. Franklin,Laurence Arend,Donald Bergsma,Lance Turkish,Paul Beer,Denis Carroll,Edgar Thomas,Thomas C. Burton,Gary W. Abrams,Hak-Joong Kim,George A. Williams,Trexler M. Topping,Frederick H. Reeser,Thomas M. Aaberg,Gregory S. Brinton,James K. Kingham,Travis A. Meredith,Raymond R. Margherio,Patrick L. Murphy,Morton S. Cox,Michael T. Trese,Steven Winokur,Everett Ai,Robert Sorenson,Gary Arsham,John Cavender,Stanley M. Kopelow,Alan L. Shabo,Jose C. Briones,Richard D. Hornichter,Norman P. Blair,Morton F. Goldberg,C. Ronald Lindberg,Neil L. Ross,Lynn E. Hauser,Jose Cunha-Vaz,J. Terry Ernest,James C. Liang,Steven B. Cohen,Charles Vygantas,Gerald A. Williams,Harry W. Flynn,George W. Blankenship,William H. Knobloch,Robert C. Ramsay,Herbert L. Cantrill,Frederick C. Goetz,Byron J. Hoogwerf,José Berrocal,Raúl Pérez,A. Ramos Umpierre,James L. Kinyoun,Robert E. Kalina,Craig G. Wells,Steven V. Guzak,Jerry P. Palmer,Frank L. Myers,George H. Bresnick,Suresh R. Chandra,Matthew D. Davis,Ronald Klein,Thomas S. Stevens,Ingolf H. L. Wallow,Russell M. Dixon,Edward Ehrlich,Robin Ewart,Robert N. Frank,Stephenie Lucas,Fred W. Whitehouse,Harold B. Weiss,Ann E. Ballen,Michael Teske,Maria Warth,William E. Benson,William S. Tasman,Gary C. Brown,J. Archibald McNamara,Hunter L. Little,Robert L. Jack,Lawrence Basso,Dayton T. Miller,Elaine W. Gunter,David D. Bayse,W. Harry Hannon,James E. Myrick,Genell L. Knatterud,Marian R. Fisher,Mary Jane Prior,Franca Barton,Joseph A. Kufera,Thomas W. Miller,James K. Hooper,Richard S. Crow,Richard Baker,Ronald J. Prineas,Larry D. Hubbard,Yvonne L. Magli,Paul Segal,Richard L. Mowery,Emily Y. Chew,Daniel Seigel,Gary Cassel +147 more
TL;DR: The early treatment diabetic retinopathy study (ETDRS) as mentioned in this paper was a randomized clinical trial of aspirin vs placebo, which was sponsored by the National Eye Institute (NIEI).
Journal ArticleDOI
Congenital Pits of the Optic Nerve Head: II. Clinical Studies in Humans
TL;DR: The clinical characteristics of 75 eyes with congenital pits of the optic nerve head were reviewed, particularly in relation to associated serous retinal detachment as discussed by the authors, and clinical evidence was presented supporting the theory that the associated subretinal fluid is derived from liquified vitreous.
Journal ArticleDOI
Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy.
TL;DR: The study documents increased levels of basic fibroblast growth factor in vitreous specimens from patients with proliferative diabetic retinopathy, particularly those with active proliferative Retinopathy.
Journal ArticleDOI
Outcomes and risk factors associated with endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents.
Chirag P. Shah,Sunir J. Garg,James F. Vander,Gary C. Brown,Richard S. Kaiser,Julia A. Haller +5 more
TL;DR: Most patients in whom presumed infectious endophthalmitis develop after anti-VEGF injection regained baseline vision after treatment, and a low threshold for vitreous tap with intravitreal antibiotic injection may be warranted.