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Yanming Li

Researcher at University of Michigan

Publications -  38
Citations -  1988

Yanming Li is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Feature selection. The author has an hindex of 10, co-authored 36 publications receiving 1700 citations. Previous affiliations of Yanming Li include University of Kansas.

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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Lam C. Tsoi, +215 more
- 01 Dec 2012 - 
TL;DR: A meta-analysis of genome-wide association studies and independent data sets genotyped on the Immunochip identified 15 new susceptibility loci, increasing to 36 the number associated with psoriasis in European individuals, and identified five independent signals within previously known loci.
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Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration

Wei Chen, +69 more
TL;DR: A genome-wide association scan for age-related macular degeneration (AMD) showed that 329 of 331 individuals with the highest-risk genotypes were cases, and 85% of these had advanced AMD, consistent with the hypothesis that HDL metabolism is associated with AMD pathogenesis.
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Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture

TL;DR: A genome-wide association study to discern differences in genetic risk factors for PsA and cutaneous-only psoriasis (PsC) and finds multiple independent susceptibility variants in the IL12B, NOS2, and IFIH1 regions.
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Multivariate sparse group lasso for the multivariate multiple linear regression with an arbitrary group structure

TL;DR: The method is able to effectively remove unimportant groups as well as unimportant individual coefficients within important groups, particularly for large p small n problems, and is flexible in handling various complex group structures such as overlapping or nested or multilevel hierarchical structures.