Georg Zeller

TL;DR: The findings indicate that HIV gut microbiome studies must control for HIV risk factors and suggest interventions on gut bacterial richness as possible novel avenues to improve HIV-1-associated immune dysfunction.

TL;DR: By using cell-specific, whole-genome profiling strategies, a large number of novel transcripts are detected and high-resolution gene expression maps are produced that provide a basis for establishing the roles of individual genes in cellular differentiation.

TL;DR: mOTUs2, an updated and functionally extended profiling tool for microbial abundance, activity and population profiling, shows that mOTUs, which are based on essential housekeeping genes, are demonstrably well-suited for quantification of basal transcriptional activity of community members.

TL;DR: Evidence is found for a vast majority of oral species to be transferable, with increased levels of transmission in colorectal cancer and rheumatoid arthritis patients and, more generally, for species described as opportunistic pathogens.

TL;DR: Accumulating evidence indicates that the gut microbiota affects colorectal cancer development, but previous studies have varied in population, technical methods, and associations with cancer, so comparisons within and between population comparisons are needed to identify sources of variation and disease associations that can be reproduced despite these variations.