G
George M. Weinstock
Researcher at Washington University in St. Louis
Publications - 488
Citations - 158810
George M. Weinstock is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 122, co-authored 482 publications receiving 144274 citations. Previous affiliations of George M. Weinstock include University of Texas at Austin & Memorial Sloan Kettering Cancer Center.
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Journal ArticleDOI
Chromosome rearrangement and diversification of Francisella tularensis revealed by the type B (OSU18) genome sequence.
Joseph F. Petrosino,Qin Xiang,Sandor E. Karpathy,Huaiyang Jiang,Shailaja Yerrapragada,Yamei Liu,Jason Gioia,Lisa Hemphill,Arely Gonzalez,T. M. Raghavan,Akif Uzman,George E. Fox,Sarah K. Highlander,Mason V. Reichard,Rebecca J. Morton,Kenneth D. Clinkenbeard,George M. Weinstock +16 more
TL;DR: The complete genome sequence and annotation for a low-passage type B strain (OSU18) isolated from a dead beaver found near Red Rock, Okla., in 1978 is reported.
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Whole-Genome Analyses of Enterococcus faecium Isolates with Diverse Daptomycin MICs
Lorena Diaz,Truc T. Tran,Jose M. Munita,William R. Miller,Sandra Rincon,Lina P Carvajal,Aye Wollam,Jinnethe Reyes,Diana Panesso,Diana Panesso,Natalia L. Rojas,Yousif Shamoo,Barbara E. Murray,George M. Weinstock,Cesar A. Arias +14 more
TL;DR: The presence of changes in 43 predicted proteins previously associated with DAP resistance in enterococci and staphylococci using the genomes of 19 E. faecium using DAP MICs above the susceptibility breakpoint suggests that genotypic information may be crucial to predict response to DAP plus β-lactam combinations.
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Exploration of bacterial community classes in major human habitats
Yanjiao Zhou,Kathie A. Mihindukulasuriya,Hongyu Gao,Patricio S. La Rosa,Kristine M. Wylie,John Martin,Karthik Kota,William D. Shannon,Makedonka Mitreva,Erica Sodergren,Erica Sodergren,George M. Weinstock,George M. Weinstock +12 more
TL;DR: An analysis of the groupings of bacterial communities in stool, nasal, skin, vaginal and oral habitats in a healthy cohort of 236 subjects from the Human Microbiome Project strengthens the understanding of the variability and dynamics of human microbiomes.
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Hydrolysis of nucleoside triphosphates catalyzed by the recA protein of Escherichia coli. Steady state kinetic analysis of ATP hydrolysis.
TL;DR: ADP, UTP, dTTP, and GTP are competitive inhibitors of the ATPase activity of recA protein, indicating that there is a single binding site for nucleoside triphosphates and thus can contribute to the cooperative effect of ATP.
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Symbiotic organs shaped by distinct modes of genome evolution in cephalopods.
Mahdi Belcaid,Giorgio Casaburi,Sarah J McAnulty,Hannah Schmidbaur,Andrea M. Suria,Silvia Moriano-Gutierrez,M. Sabrina Pankey,Todd H. Oakley,Natacha Kremer,Eric J. Koch,Andrew Collins,Hoan Nguyen,Sai Lek,Irina Goncharenko-Foster,Patrick Minx,Erica Sodergren,George M. Weinstock,Daniel S. Rokhsar,Daniel S. Rokhsar,Daniel S. Rokhsar,Margaret J. McFall-Ngai,Oleg Simakov,Oleg Simakov,Jamie S. Foster,Spencer V. Nyholm +24 more
TL;DR: The genome of Euprymna scolopes, a model cephalopod with richly characterized host–microbe interactions, is analyzed and genomic signatures of host–symbiont interactions are revealed, suggesting that the two symbiotic organs within E. scolope originated by different evolutionary mechanisms.