G
George M. Weinstock
Researcher at Washington University in St. Louis
Publications - 488
Citations - 158810
George M. Weinstock is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 122, co-authored 482 publications receiving 144274 citations. Previous affiliations of George M. Weinstock include University of Texas at Austin & Memorial Sloan Kettering Cancer Center.
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Identification and phenotypic characterization of a second collagen adhesin, Scm, and genome-based identification and analysis of 13 other predicted MSCRAMMs, including four distinct pilus loci, in Enterococcus faecium.
Jouko Sillanpää,Sreedhar R. Nallapareddy,Vittal P. Prakash,Xiang Qin,Magnus Höök,George M. Weinstock,Barbara E. Murray +6 more
TL;DR: The draft genome of strain TX0016 was analysed for potential microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) and 22 predicted cell-wall-anchored E. faecium surface proteins, of which 15 had characteristics typical of MSCRAMMs, including predicted folding into a modular architecture with multiple immunoglobulin-like domains.
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DNA sequence of the Pasteurella haemolytica leukotoxin gene cluster.
TL;DR: Bovine serum was used to identify a recombinant phage clone carrying the Pasteurella haemolytica leukotoxin gene, and in the presence of the alpha-hemolysin genes, the leukOToxin was secreted into the medium, demonstrating functional complementation by the hemolysin secretory system.
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NIH working group report—using genomic information to guide weight management: From universal to precision treatment
Molly S. Bray,Ruth J. F. Loos,Jeanne M. McCaffery,Charlotte Ling,Paul W. Franks,George M. Weinstock,Michael Snyder,Jason L. Vassy,Tanya Agurs-Collins +8 more
TL;DR: A large number of patients with common, complex conditions like obesity, inflammation, and insulin resistance, which underlie a host of metabolic diseases are being treated with genome-based approaches.
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A Cluster of Genes Involved in Polysaccharide Biosynthesis from Enterococcus faecalis OG1RF
TL;DR: This is the first report on a gene cluster of E. faecalisinvolved in the biosynthesis of an antigenic polysaccharide involved in the export of sugar polymers from both gram-positive and gram-negative organisms.
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Leucoagaricus gongylophorus produces diverse enzymes for the degradation of recalcitrant plant polymers in leaf-cutter ant fungus gardens.
Frank O. Aylward,Kristin E. Burnum-Johnson,Susannah G. Tringe,Clotilde Teiling,Daniel M. Tremmel,Joseph A. Moeller,Joseph A. Moeller,Jarrod J. Scott,Jarrod J. Scott,Kerrie Barry,Paul D. Piehowski,Carrie D. Nicora,Stephanie Malfatti,Matthew E. Monroe,Samuel O. Purvine,Lynne Goodwin,Richard D. Smith,George M. Weinstock,Nicole M. Gerardo,Garret Suen,Mary S. Lipton,Cameron R. Currie,Cameron R. Currie,Cameron R. Currie +23 more
TL;DR: This study provides a detailed analysis of plant biomass degradation in leaf-cutter ant fungus gardens and insight into the enzymes underlying the symbiosis between these dominant herbivores and their obligate fungal cultivar.