G
George M. Weinstock
Researcher at Washington University in St. Louis
Publications - 488
Citations - 158810
George M. Weinstock is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 122, co-authored 482 publications receiving 144274 citations. Previous affiliations of George M. Weinstock include University of Texas at Austin & Memorial Sloan Kettering Cancer Center.
Papers
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Journal ArticleDOI
Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching
Lori A. S. Snyder,Lori A. S. Snyder,Nicholas J. Loman,James D. Linton,Rebecca Langdon,George M. Weinstock,Brendan W. Wren,Mark J. Pallen +7 more
TL;DR: This work has identified coding regions in the genome sequence of Helicobacter canadensis that show variations in homopolymeric tract length in the bacterial population, indicative of phase variation, and these regions are potentially associated with promoter regions, which would lead to transcriptional phase variation.
Journal ArticleDOI
Sensitization of bacteria to danofloxacin by temperate prophages.
TL;DR: Killing studies against the bovine pathogen Pasteurella haemolytica demonstrated that danofloxacin exhibits particularly rapid killing kinetics, and lysogenic Escherichia coli bearing lambda is found to be more sensitive to dan ofloxAcin than nonlysogenic E. coli.
Journal ArticleDOI
Static DNA bending and protein interactions within the Pasteurella haemolytica leukotoxin promoter region : development of an activation model for leukotoxin transcriptional control
TL;DR: The arrangement of these elements suggests that leukotoxin expression is activated by a factor that interacts with the UAS and regulates transcription initiation at a distance via DNA looping.
Book ChapterDOI
Identification of Virulence Genes in Silico: Infectious Disease Genomics
TL;DR: Methods to identify virulence factors can rely on classic genetic approaches as well as homology searches and other genome-wide analyses such as comparative genomics, which confirm the importance of the genes and identify which genes contribute to the differences between these two infections.
Journal ArticleDOI
Erratum to: The real cost of sequencing: scaling computation to keep pace with data generation
Paul R. Muir,Shantao Li,Shaoke Lou,Daifeng Wang,Daniel Spakowicz,Leonidas Salichos,Jing Zhang,George M. Weinstock,Farren J. Isaacs,Joel Rozowsky,Mark Gerstein +10 more
TL;DR: The number of faculty position hires at 51 US universities in 3-year bins and the recent increase in hiring coincides with the explosion in sequencing data.