George M. Weinstock

TL;DR: By analyzing multi-tissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, a transcriptome resource is generated and the first catalogue of expression quantitative trait loci (eQTLs) in a non-human primate model is produced.

TL;DR: This paper proposes and applies a new regression model combining the Dirichlet-multinomial distribution with recursive partitioning providing a fully non-parametric regression model, called DM-RPart, which is applied to cytokine data and microbiome taxa count data and is applicable to any microbiomeTaxa count/metadata, is automatically fit, and intuitively interpretable.

TL;DR: Three strains ofEscherichia fergusonii (EF873, EF1496, EF939) of 50 strains tested produced the hydroxamate siderophore aerobactin, suggesting that E. f Fergusonii iucABCD iutA genes are a portion of a larger segment of DNA similar to pathogenicity islands of other bacteria.

TL;DR: This article focuses on the following two key innovations in mapping and sequencing: first, shotgun sequencing of clone pools to combine the benefits of whole-genome shotgun and clone-by-clone strategies, and the leveraging of newly available assembled genomic sequences to improve the effectiveness of new sequencing projects through comparative mapping and comparative sequence assembly.

TL;DR: The authors observed a reduction in risk of islet autoimmunity in the children who had received dietary supplements of probiotics at or before age 27 days compared with those who first received probiotics after 27 days of life, suggesting early exposure to supplemental probiotics may decrease the risk of IA among children at elevated risk of T1DM.