G
George M. Weinstock
Researcher at Washington University in St. Louis
Publications - 488
Citations - 158810
George M. Weinstock is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 122, co-authored 482 publications receiving 144274 citations. Previous affiliations of George M. Weinstock include University of Texas at Austin & Memorial Sloan Kettering Cancer Center.
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Journal ArticleDOI
Novel Bacterial Taxa in the Human Microbiome
Kristine M. Wylie,Rebecca Truty,Thomas J. Sharpton,Kathie A. Mihindukulasuriya,Yanjiao Zhou,Hongyu Gao,Erica Sodergren,George M. Weinstock,Katherine S. Pollard +8 more
TL;DR: A rigorous bioinformatics pipeline is established that uses sequence data from multiple platforms and approaches and approaches (whole-genome shotgun and 16S rDNA amplicons) to validate novel taxa to identify low-abundance, novel bacterial taxa which span three major phyla in the bacterial tree of life.
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A Novel Treponema pallidum Antigen, TP0136, Is an Outer Membrane Protein That Binds Human Fibronectin
Mary Beth Brinkman,Melanie A. McGill,Jonas Pettersson,Arthur Rogers,Petra Matějková,David Šmajs,George M. Weinstock,Steven J. Norris,Timothy Palzkill +8 more
TL;DR: It is demonstrated that TP0136 is expressed on the outer membrane of the treponeme during infection and may be involved in attachment to host extracellular matrix components.
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Repetitive Sequence-Based PCR versus Pulsed-Field Gel Electrophoresis for Typing of Enterococcus faecalis at the Subspecies Level
TL;DR: Repetitive sequence-based PCR was compared to pulsed-field gel electrophoresis (PFGE) for the ability to discriminateEnterococcus faecalis isolates at the subspecies level and results were more difficult to interpret than PFGE results.
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Evidence that the enterococcal polysaccharide antigen gene (epa) cluster is widespread in Enterococcus faecalis and influences resistance to phagocytic killing of E. faecalis.
TL;DR: The results indicate that the epa gene cluster is widespread among E. faecalis and confers some protection against human host defenses.
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Whole-Genome Analysis of a Daptomycin-Susceptible Enterococcus faecium Strain and Its Daptomycin-Resistant Variant Arising during Therapy
Truc T. Tran,Diana Panesso,Diana Panesso,Hongyu Gao,Jung Hyeob Roh,Jose M. Munita,Jose M. Munita,Jinnethe Reyes,Jinnethe Reyes,Lorena Diaz,Lorena Diaz,Elizabeth A. Lobos,Elizabeth A. Lobos,Yousif Shamoo,Nagendra N. Mishra,Arnold S. Bayer,Barbara E. Murray,George M. Weinstock,Cesar A. Arias +18 more
TL;DR: The results suggest that, apart from the LiaFSR system, the essential YycFG system is likely to be an important mediator of DAP resistance in some E. faecium strains.