G
George M. Weinstock
Researcher at Washington University in St. Louis
Publications - 488
Citations - 158810
George M. Weinstock is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 122, co-authored 482 publications receiving 144274 citations. Previous affiliations of George M. Weinstock include University of Texas at Austin & Memorial Sloan Kettering Cancer Center.
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Deciphering Functional Redundancy in the Human Microbiome
Liang Tian,Xu-Wen Wang,Ang Kun Wu,Ang Kun Wu,Yuhang Fan,Yuhang Fan,Jonathan Friedman,Amber Dahlin,Matthew K. Waldor,Matthew K. Waldor,George M. Weinstock,Scott Weiss,Yang-Yu Liu +12 more
TL;DR: In this paper, the authors investigate the basis for functional redundancy in the human microbiome by analyzing its genomic content network, a bipartite graph that links microbes to the genes in their genomes, and find that this network exhibits several topological features that favor high functional redundancy.
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The Gut Microbiome and Substance Use Disorder.
TL;DR: A review of animal and clinical evidence that the gut microbiome is involved in substance use disorders can be found in this paper, where the authors discuss the underlying mechanisms by which the Gut microbiome interacts with SUD through metabolomic, immune, neurological, and epigenetic mechanisms.
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Recognition of pore-forming colicin Y by its cognate immunity protein.
TL;DR: Construction of hybrid immunity genes between colicin U (cui) and Y (cyi) immunity genes and site-directed mutagenesis of cyi were used to identify amino-acid residues of the Colicin Y immunity protein (Cyi) involved in recognition of colicIn Y.
Journal Article
Automated determination of beta-galactosidase specific activity.
TL;DR: This work describes a modification of an automated kinetic assay for beta-galactosidase (beta-gal) activity that includes an assay to quantitate the amount of protein added to each assay and presents a series of macros written in Microsoft Excel to decrease theamount of time required to analyze the data from Beta-gal assays.
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Differences in Gut Microbiome in Hospitalized Immunocompetent vs. Immunocompromised Children, Including Those With Sickle Cell Disease.
Sindhu Mohandas,Sindhu Mohandas,Sindhu Mohandas,Vijaya L. Soma,Vijaya L. Soma,Thi Dong Binh Tran,Erica Sodergren,Tresa Ambooken,David L. Goldman,David L. Goldman,George M. Weinstock,Betsy C. Herold,Betsy C. Herold +12 more
TL;DR: Antibiotics and proton pump inhibitors, which were more commonly used in IC children, were identified as risk factors for lower microbial diversity and non-IC patients had higher abundance of several bacterial species associated with health.