G
George M. Weinstock
Researcher at Washington University in St. Louis
Publications - 488
Citations - 158810
George M. Weinstock is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 122, co-authored 482 publications receiving 144274 citations. Previous affiliations of George M. Weinstock include University of Texas at Austin & Memorial Sloan Kettering Cancer Center.
Papers
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GENOME ANNOUNCEMENT Genome Sequence of the Emerging Pathogen Helicobacter canadensis
Nicholas J. Loman,Lori A. S. Snyder,James D. Linton,Rebecca Langdon,Andrew J. Lawson,George M. Weinstock,Brendan W. Wren,Mark J. Pallen +7 more
TL;DR: In this paper, the authors determined the genome sequence of the type strain of Helicobacter canadensis, an emerging human pathogen with diverse animal reservoirs, including systems for N-linked glycosylation and capsular export.
Journal ArticleDOI
A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice.
Jason A. Bubier,Vivek M. Philip,Vivek M. Philip,Christopher Quince,James H. Campbell,James H. Campbell,Yanjiao Zhou,Tatiana A. Vishnivetskaya,Tatiana A. Vishnivetskaya,Suman Duvvuru,Suman Duvvuru,Rachel Blair,Juliet Ndukum,Kevin D. Donohue,Carmen M. Foster,David J. Mellert,George M. Weinstock,Cymbeline T. Culiat,Cymbeline T. Culiat,Bruce F. O'Hara,Anthony V. Palumbo,Mircea Podar,Elissa J. Chesler,Elissa J. Chesler +23 more
TL;DR: Using a highly diverse mouse population, Bubier et al. identified that Odoribacter abundance influences sleep archi-tecture in a manner that can be used to interrogate other diseases, microbes, and mechanisms.
Posted ContentDOI
Ancient hybridization and strong adaptation to viruses across African vervet monkey populations
Hannes Svardal,Hannes Svardal,Anna J. Jasinska,Cristian Apetrei,Giovanni Coppola,Yu S. Huang,Christopher A. Schmitt,Beatrice Jacquelin,Michaela Müller-Trutwin,George M. Weinstock,J. Paul Grobler,Richard K. Wilson,Trudy R. Turner,Wesley C. Warren,Nelson B. Freimer,Magnus Nordborg +15 more
TL;DR: High diversity, within and between taxa, and clear evidence that taxonomic divergence was reticulate rather than following a simple branching pattern are found, and selection in vervets appears to have primarily targeted genes involved in the transcriptional regulation of viruses, suggesting adaptation to living with SIV rather than defense against infection.
Patent
VMP-like sequences of pathogenic Borrelia
Steven J. Norris,Jing-Ren Zhang,John M. Hardham,Jerrilyn K. Howell,Alan G. Barbour,George M. Weinstock +5 more
TL;DR: The use of DNA sequences encoding VMP-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors, the encoded amino acid sequences, and the application of DNA and amino acids sequences to the production of polypeps as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis was discussed in this paper.
Book ChapterDOI
Hypothesis Testing of Metagenomic Data
TL;DR: This chapter presents statistical methods for analyzing metagenomic taxonomic data and determining the sample size for experiments in order to ensure sufficient power to detect a difference in microbiomes.