G
George M. Weinstock
Researcher at Washington University in St. Louis
Publications - 488
Citations - 158810
George M. Weinstock is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 122, co-authored 482 publications receiving 144274 citations. Previous affiliations of George M. Weinstock include University of Texas at Austin & Memorial Sloan Kettering Cancer Center.
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Journal ArticleDOI
Epidemiology of Staphylococcus aureus during space flight.
Duane L. Pierson,Monjula Chidambaram,J D Heath,Laura L. Mallary,Saroj K. Mishra,Baldev Sharma,George M. Weinstock +6 more
TL;DR: Staphylococcus aureus was isolated over 2 years from Space Shuttle mission crewmembers to determine dissemination and retention of bacteria as mentioned in this paper, and DNA fingerprinting of samples by digestion of DNA with SmaI restriction endonuclease followed by pulsed-field gel electrophoresis showed S. auresus from each crewmember had a unique fingerprint and usually only one strain was carried by an individual.
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A novel intronic single nucleotide polymorphism in the myosin heavy polypeptide 4 gene is responsible for the mini-muscle phenotype characterized by major reduction in hind-limb muscle mass in mice.
Scott A. Kelly,Timothy A. Bell,Sarah R. Selitsky,Ryan J. Buus,Kunjie Hua,George M. Weinstock,Theodore Garland,Fernando Pardo-Manuel de Villena,Daniel Pomp +8 more
TL;DR: In this article, the authors identify the SNP representing a C-to-T transition located in a 709-bp intron between exons 11 and 12 of the Myosin heavy polypeptide 4 (Myh4) skeletal muscle gene (position 67,244,850 on MMU11).
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Coverage theories for metagenomic DNA sequencing based on a generalization of Stevens’ theorem
TL;DR: An approach based upon a generalization of Stevens’ Theorem for randomly covering a domain is proposed, extending this result to account for the presence of multiple species, from which are derived useful probabilities for fully recovering a particular target microbe of interest and for average contig length.
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HCoDES Reveals Chromosomal DNA End Structures with Single-Nucleotide Resolution.
Yair Dorsett,Yanjiao Zhou,Anthony T. Tubbs,Bo-Ruei Chen,Caitlin E. Purman,Baeck-Seung Lee,Rosmy George,Andrea L. Bredemeyer,Jiang-yang Zhao,Erica Sodergen,George M. Weinstock,Nathan D. Han,Alejandro Reyes,Eugene M. Oltz,Dale Dorsett,Ziva Misulovin,Jacqueline E. Payton,Barry P. Sleckman +17 more
TL;DR: The high-resolution end structures obtained by HCoDES identify features of DNA end processing during DSB repair, which suggests that H2AX and 53BP1 may have distinct activities in end protection.
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Increased production of colicin E1 in stationary phase.
TL;DR: The expression of cea-lacZ fusions was found to be stimulated when cells reached stationary phase and the data were consistent with this increase being independent of the SOS response, anaerobiosis, catabolite repression, and integration host factor as well as the stationary-phase regulators encoded by rpoS and lrp.