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Giulia Petroni
Researcher at Cornell University
Publications - 21
Citations - 1378
Giulia Petroni is an academic researcher from Cornell University. The author has contributed to research in topics: Autophagy & Cancer cell. The author has an hindex of 8, co-authored 21 publications receiving 303 citations. Previous affiliations of Giulia Petroni include University of Florence.
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Journal ArticleDOI
Autophagy in major human diseases
Daniel J. Klionsky,Giulia Petroni,Ravi K. Amaravadi,Eric H. Baehrecke,Andrea Ballabio,Andrea Ballabio,Patricia Boya,José Manuel Bravo-San Pedro,Ken Cadwell,Francesco Cecconi,Francesco Cecconi,Augustine M.K. Choi,Augustine M.K. Choi,Mary E. Choi,Mary E. Choi,Charleen T. Chu,Patrice Codogno,Patrice Codogno,María Isabel Colombo,Ana Maria Cuervo,Vojo Deretic,Ivan Dikic,Zvulun Elazar,Eeva-Liisa Eskelinen,Gian Maria Fimia,David A. Gewirtz,Douglas R. Green,Malene Hansen,Marja Jäättelä,Terje Johansen,Gábor Juhász,Vassiliki Karantza,Claudine Kraft,Guido Kroemer,Nicholas T. Ktistakis,Sharad Kumar,Sharad Kumar,Carlos López-Otín,Kay F. Macleod,Frank Madeo,Jennifer Martinez,Alicia Meléndez,Alicia Meléndez,Noboru Mizushima,Christian Münz,Josef M. Penninger,Josef M. Penninger,Rushika M. Perera,Mauro Piacentini,Mauro Piacentini,Fulvio Reggiori,David C. Rubinsztein,Kevin M. Ryan,Junichi Sadoshima,Laura Santambrogio,Luca Scorrano,Hans-Uwe Simon,Hans-Uwe Simon,Anna Katharina Simon,Anne Simonsen,Anne Simonsen,Alexandra Stolz,Nektarios Tavernarakis,Nektarios Tavernarakis,Sharon A. Tooze,Tamotsu Yoshimori,Junying Yuan,Junying Yuan,Zhenyu Yue,Qing Zhong,Lorenzo Galluzzi,Federico Pietrocola +71 more
TL;DR: In this paper, preclinical data linking autophagy dysfunction to the pathogenesis of major human disorders including cancer as well as cardiovascular, neurodegenerative, metabolic, pulmonary, renal, infectious, musculoskeletal, and ocular disorders.
Journal ArticleDOI
Detection of immunogenic cell death and its relevance for cancer therapy
Jitka Fucikova,Oliver Kepp,Lenka Kasikova,Giulia Petroni,Takahiro Yamazaki,Peng Liu,Liwei Zhao,Radek Spisek,Guido Kroemer,Lorenzo Galluzzi,Lorenzo Galluzzi +10 more
TL;DR: Qualitative approaches for measuring ICD markers in vitro and ex vivo for the discovery of next-generation antineoplastic agents, the development of personalized anticancer regimens, and the identification of optimal therapeutic combinations for the clinical management of cancer are outlined.
Journal ArticleDOI
Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy.
Takahiro Yamazaki,Alexander Kirchmair,Ai Sato,Aitziber Buqué,Marissa Rybstein,Giulia Petroni,Norma Bloy,Francesca Finotello,Lena Stafford,Esther Navarro Manzano,Francisco Ayala de la Peña,Elena García-Martínez,Silvia C. Formenti,Zlatko Trajanoski,Lorenzo Galluzzi +14 more
TL;DR: It is shown that tumor cell autophagy opposes inflammatory cell death following radiation therapy and can be inhibited to enhance antitumor responses, suggesting that mitochondrial outer membrane permeabilization may represent a valid target for boosting radiation therapy immunogenicity in patients with breast cancer.
Journal ArticleDOI
Immunomodulation by targeted anticancer agents
TL;DR: The main immunomodulatory effects of targeted anticancer agents are discussed and potential avenues to harness them in support of superior clinical efficacy are explored.
Journal ArticleDOI
Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients
Maria E. Rodriguez-Ruiz,Maria E. Rodriguez-Ruiz,Aitziber Buqué,Michal Hensler,Jonathan Chen,Norma Bloy,Giulia Petroni,Giulia Petroni,Ai Sato,Takahiro Yamazaki,Jitka Fucikova,Lorenzo Galluzzi +11 more
TL;DR: It is reported that mouse mammary carcinoma TSA cells lacking Casp3 or subjected to chemical caspase inhibition were as sensitive to the cytostatic and cytotoxic effects of radiation therapy in vitro as their control counterparts, yet secreted increased levels of type I IFN.