H
Hai-Lin Wang
Researcher at Center for International Blood and Marrow Transplant Research
Publications - 55
Citations - 1738
Hai-Lin Wang is an academic researcher from Center for International Blood and Marrow Transplant Research. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 19, co-authored 54 publications receiving 1257 citations. Previous affiliations of Hai-Lin Wang include Medical College of Wisconsin.
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Journal ArticleDOI
Nonpermissive HLA-DPB1 mismatch increases mortality after myeloablative unrelated allogeneic hematopoietic cell transplantation
Joseph Pidala,Stephanie J. Lee,Kwang Woo Ahn,Stephen R. Spellman,Hai-Lin Wang,Mahmoud Aljurf,Medhat Askar,Jason Dehn,Marcelo A. Fernandez Viña,Alois Gratwohl,Vikas Gupta,Rabi Hanna,Mary M. Horowitz,Carolyn Katovich Hurley,Yoshihiro Inamoto,Adetola A. Kassim,Taiga Nishihori,Carlheinz Mueller,Machteld Oudshoorn,Effie W. Petersdorf,Vinod K. Prasad,James Robinson,James Robinson,Wael Saber,Kirk R. Schultz,Bronwen E. Shaw,Bronwen E. Shaw,Jan Storek,William A. Wood,Ann E. Woolfrey,Claudio Anasetti +30 more
TL;DR: Current outcomes of unrelated donor allogeneic hematopoietic cell transplantation (HCT) is examined to determine the clinical implications of donor-recipient HLA matching, and full matching at HLA-A, -B, -C, and -DRB1 is required for optimal unrelated donor HCT survival.
Journal ArticleDOI
Survival of Patients with Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Cell Transplantation: A Center for International Blood and Marrow Transplant Research Study
Nelli Bejanyan,Daniel J. Weisdorf,Brent R. Logan,Brent R. Logan,Hai-Lin Wang,Steven M. Devine,Marcos de Lima,Donald Bunjes,Mei-Jie Zhang +8 more
TL;DR: The authors studied outcomes of 1788 acute myeloid leukemia patients relapsing after allogeneic hematopoietic cell transplantation (alloHCT) during first or second complete remission (CR) to identify factors associated with longer post-relapse survival.
Journal ArticleDOI
Ph+ ALL patients in first complete remission have similar survival after reduced intensity and myeloablative allogeneic transplantation: impact of tyrosine kinase inhibitor and minimal residual disease
Veronika Bachanova,David I. Marks,Mei-Jie Zhang,Hai-Lin Wang,M. de Lima,Mahmoud Aljurf,Martha Arellano,Andrew S. Artz,Ulrike Bacher,Jean-Yves Cahn,Yi-Bin Chen,Edward A. Copelan,William R. Drobyski,Robert Peter Gale,John P. Greer,Vikas Gupta,Gregory A. Hale,Partow Kebriaei,Hillard M. Lazarus,Ian D. Lewis,Victor Lewis,Jane L. Liesveld,Mark R. Litzow,Alison W. Loren,Alan M. Miller,Maxim Norkin,Betul Oran,Joseph Pidala,Jacob M. Rowe,Bipin N. Savani,Wael Saber,Ravi Vij,Edmund K. Waller,Peter H. Wiernik,Daniel J. Weisdorf +34 more
TL;DR: RIC is a valid alternative strategy for Ph+ ALL patients ineligible for MAC and MRDneg status is preferred pre-HCT.
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Development of an Unrelated Donor Selection Score Predictive of Survival after HCT: Donor Age Matters Most.
Bronwen E. Shaw,Brent R. Logan,Stephen R. Spellman,Steven G.E. Marsh,James Robinson,Joseph Pidala,Carolyn Katovich Hurley,Juliet N. Barker,Martin Maiers,Jason Dehn,Hai-Lin Wang,Mike Haagenson,David L. Porter,Effie W. Petersdorf,Ann E. Woolfrey,Mary M. Horowitz,Michael R. Verneris,Katharine C. Hsu,Katharina Fleischhauer,Stephanie J. Lee,Stephanie J. Lee +20 more
TL;DR: The only donor characteristic associated with better survival was younger age, with 2-year survival being 3% better when a donor 10 years younger is selected, and hence flexibility in selecting URDs based on other characteristics is justified.
Journal ArticleDOI
HLA Mismatch Is Associated with Worse Outcomes after Unrelated Donor Reduced-Intensity Conditioning Hematopoietic Cell Transplantation: An Analysis from the Center for International Blood and Marrow Transplant Research
Michael R. Verneris,Stephanie J. Lee,Kwang Woo Ahn,Hai-Lin Wang,Minoo Battiwalla,Yoshihiro Inamoto,Marcelo Fernandez-Vina,James Gajewski,Joseph Pidala,Reinhold Munker,Mahmoud Aljurf,Wael Saber,Stephen R. Spellman,John Koreth +13 more
TL;DR: Although feasible, single-locus mismatch in RIC URD HCT is associated with inferior outcomes; in subgroup analysis, inferior transplant outcomes were noted regardless of the HLA allele mismatched.