H
Hiroshi Inoue
Researcher at University of Tokushima
Publications - 47
Citations - 2064
Hiroshi Inoue is an academic researcher from University of Tokushima. The author has contributed to research in topics: Haplotype & Single-nucleotide polymorphism. The author has an hindex of 24, co-authored 47 publications receiving 1928 citations.
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Journal ArticleDOI
Recessive Mutations in the Putative Calcium-Activated Chloride Channel Anoctamin 5 Cause Proximal LGMD2L and Distal MMD3 Muscular Dystrophies
V. Bolduc,Gareth Marlow,Kym M. Boycott,Khalil Saleki,Hiroshi Inoue,Johan T.M. Kroon,Mitsuo Itakura,Yves Robitaille,Lucie Parent,Frank Baas,Kuniko Mizuta,Nobuyuki Kamata,Isabelle Richard,W. H. J. P. Linssen,Ibrahim Mahjneh,Marianne de Visser,Rumaisa Bashir,Bernard Brais +17 more
TL;DR: Though the function of the ANO5 protein is still unknown, its putative calcium-activated chloride channel function may lead to important insights into the role of deficient skeletal muscle membrane repair in muscular dystrophies.
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The Novel Gene Encoding a Putative Transmembrane Protein Is Mutated in Gnathodiaphyseal Dysplasia (GDD)
Satoshi Tsutsumi,Nobuyuki Kamata,Tamara Vokes,Yutaka Maruoka,Koichi Nakakuki,Shoji Enomoto,Ken Omura,Teruo Amagasa,Masaru Nagayama,Fumiko Saito-Ohara,Johji Inazawa,Maki Moritani,Takashi Yamaoka,Hiroshi Inoue,Mitsuo Itakura +14 more
TL;DR: Cellular localization to the endoplasmic reticulum suggests a role for GDD1 in the regulation of intracellular calcium homeostasis and evolutionarily conserved among human, mouse, zebrafish, fruit fly, and mosquito.
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Association of STAT4 With Susceptibility to Rheumatoid Arthritis and Systemic Lupus Erythematosus in the Japanese Population
Shu Kobayashi,Katsunori Ikari,Hirotaka Kaneko,Yuta Kochi,Kazuhiko Yamamoto,Kenichi Shimane,Yusuke Nakamura,Yoshiaki Toyama,Takeshi Mochizuki,So Tsukahara,Yasushi Kawaguchi,Chihiro Terai,Masako Hara,Taisuke Tomatsu,Hisashi Yamanaka,Takahiko Horiuchi,Kayoko Tao,Koji Yasutomo,Daisuke Hamada,Natsuo Yasui,Hiroshi Inoue,Mitsuo Itakura,Hiroshi Okamoto,Naoyuki Kamatani,Shigeki Momohara +24 more
TL;DR: It is concluded that STAT4 is associated with rheumatoid arthritis and systemic lupus erythematosus in the Japanese, and is a common genetic risk factor for autoimmune diseases, with similar strength across major racial groups.
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Overexpression of HMGA2 relates to reduction of the let-7 and its relationship to clinicopathological features in pituitary adenomas
Zhi Rong Qian,Sylvia L. Asa,Haruhiko Siomi,Mikiko C. Siomi,Katsuhiko Yoshimoto,Shozo Yamada,Elaine Lu Wang,Mustafizur Rahman,Hiroshi Inoue,Mitsuo Itakura,Eiji Kudo,Toshiaki Sano +11 more
TL;DR: Findings support a causal link between let-7 and high-mobility group A2 whereby loss ofLet-7 expression induces high-Mobility groupA2 upregulation that represents an important mechanism in pituitary tumorigenesis and progression.
Journal ArticleDOI
Expression and distribution of Gpr119 in the pancreatic islets of mice and rats: Predominant localization in pancreatic polypeptide-secreting PP-cells
Yukiko Sakamoto,Hiroshi Inoue,Shuhei Kawakami,Katsuyuki Miyawaki,Tatsuro Miyamoto,Kuniko Mizuta,Mitsuo Itakura +6 more
TL;DR: The Gpr119 mRNA levels were elevated in islets of obese hyperglycemic db/db mice as compared to control islets, suggesting a possible involvement of this receptor in the development of obesity and diabetes.