H
Hiroshi Maeda
Researcher at Kumamoto University
Publications - 915
Citations - 67944
Hiroshi Maeda is an academic researcher from Kumamoto University. The author has contributed to research in topics: Neocarzinostatin & Nitric oxide. The author has an hindex of 103, co-authored 893 publications receiving 63370 citations. Previous affiliations of Hiroshi Maeda include Osaka University & Okayama University.
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Journal ArticleDOI
Spontaneous deamidation of a protein antibiotic, neocarzinostatin, at weakly acidic pH. Conversion to a homologous inactive preneocarzinostatin due to change of asparagine 83 to aspartic acid 83 accompanied by conformational and biological alterations.
Hiroshi Maeda,Kenji Kuromizu +1 more
TL;DR: The amide content of preneocarzinostatin (PRE) was determined by analysing asparagine and glutamine in the Pronase-aminopeptidase M digests of tetra-S-carboxymethyl-NCS and carboxyl-modified NCS (modified with a water-soluble carbodiimide and [14C]glycine methyl ester) as discussed by the authors.
Journal ArticleDOI
Conjugation of Cu,Zn-superoxide dismutase with succinylated gelatin: Pharmacological activity and cell-lubricating function
TL;DR: A newly added property of the conjugate is cell-lubricating activity, which facilitated cell passage through micropores and reduced hemolysis during cell passage in vitro.
Book ChapterDOI
Enhanced Permeability and Retention (EPR) Efect: Basis for Drug Targeting to Tumor
TL;DR: Polymeric drugs and microparticles, including micellar compounds or liposomes, can be delivered with greater selectivity to tumors because of the EPR effect.
Journal ArticleDOI
Processing of Ag-doped Bi2212 bulks in high magnetic fields: a strong correlation between degree of texture and field strength
TL;DR: A series of high magnetic fields up to 9 T have been applied to the preparation of Ag-doped Bi2212 bulks and a strong correlation is observed between the field strength and the degree of texture developed in the bulks.
Journal ArticleDOI
Preparation of YBa2Cu3Oy Superconducting Thin Films on Metallic Substrates by Excimer Laser Ablation
Junichi Saitoh,Masao Fukutomi,Kazunori Komori,Yoshiaki Tanaka,Toshihisa Asano,Hiroshi Maeda,Hidefusa Takahara +6 more
TL;DR: In this paper, superconducting thin films of YBa2Cu3Oy on a metallic substrate were prepared in situ by a pulsed laser ablation technique, and the growth quality of the YSZ/Hastelloy substrates with or without a Pt underlayer was compared.