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Hiroshi Maeda

Researcher at Kumamoto University

Publications -  915
Citations -  67944

Hiroshi Maeda is an academic researcher from Kumamoto University. The author has contributed to research in topics: Neocarzinostatin & Nitric oxide. The author has an hindex of 103, co-authored 893 publications receiving 63370 citations. Previous affiliations of Hiroshi Maeda include Osaka University & Okayama University.

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Transcriptional analysis of genes for energy catabolism and hydrolytic enzymes in the filamentous fungus Aspergillus oryzae using cDNA microarrays and expressed sequence tags.

TL;DR: The wheat-bran culture gave the richest gene expression profile of hydrolytic enzymes and the lowest expression levels of catabolic genes (EMP, TCA) among the three media tested, suggesting that A. oryzae uses both EMP and TCA for glucose metabolism under AC conditions.
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Potentiation of nitric oxide-mediated vasorelaxation by xanthine oxidase inhibitors

TL;DR: It seems that XO regulates EDRF/NO via production of O2 - through inhibition of xanthine oxidase in vitro by three types of pyrazolopyrimidine derivatives.
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Human matrix metalloprotease activation by insults of bacterial infection involving proteases and free radicals.

TL;DR: It is found that human matrix metalloproteases (MMPs) may be processed from their proenzyme forms (proMMP) to their active forms by two new and unique mechanisms: Firstly, by bacterial proteases such as Pseudomonas elastase and Vibrio cholerae protease, and secondly, by free radical generation by activated polymorphonuclear leukocytes.
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NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate

TL;DR: Immunocytochemical analysis of cells transfected with NGEP cDNAs containing a Myc epitope tag at the carboxyl terminus shows that the protein encoded by the short transcript is localized in the cytoplasm, whereas the protein encode by the long transcript is present on the plasma membrane.