J
Joann Belden
Researcher at Indiana University
Publications - 9
Citations - 1326
Joann Belden is an academic researcher from Indiana University. The author has contributed to research in topics: Placebo & Randomized controlled trial. The author has an hindex of 9, co-authored 9 publications receiving 1266 citations. Previous affiliations of Joann Belden include Indiana University – Purdue University Indianapolis.
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Journal ArticleDOI
A controlled trial of rasagiline in early Parkinson disease: The tempo study
Andrew Siderowf,Matthew B. Stern,Ira Shoulson,Karl Kieburtz,David Oakes,Denni Day,Aileen Shinaman,Sandra Plumb,Stanley Fahn,Karen Blindauer,Mark F. Lew,Howard I. Hurtig,Mary Lloyd,Robert A. Hauser,Lisa Gauger,Lawrence I. Golbe,Joanne Wojcieszek,Joann Belden,Andrew Feigin,Mary Lou Klimek,Barbara Shannon,William G. Ondo,Christine Hunter,Vincent Calabrese,Paul Atchison,Cathy W. Allen,Frederick J. Marshall,Debra Berry,Irenita Gardiner,Janis M. Miyasaki,Luisa Del Rizzo,Tilak Mendis,Neila Mendis,Peggy Gray,Jean P. Hubble,Karen Betcher,Rajesh Pahwa,Eric Molho,Diane Brown,Lisa M. Shulman,Ali H. Rajput,Marianne Ewanishin,Mark Stacy,Kelli Williamson,John M. Bertoni,Carolyn Peterson,Paul J. Tuite,Brenda Ebbitt,Kathleen M. Shannon,Jean A. Jaglin,Caroline M. Tanner,Kenneth Marek,Karen Stavris,Michael J. Aminoff,Mariann DiMinno,Glenna A. Dowling,Un Jung Kang,Judy Richman,Kapil D. Sethi,W.R. Wayne Martin,Pamela King,Germaine McInnes,Charles H. Adler,Peter A. LeWitt,Maryan DeAngelis,Myrna Schear,Mark Forrest Gordon,Roberta Winnick,Robert G. Feldman,Cathi A. Thomas,Kelly M. Conn,Alicia Brocht,Chris Chadwick,Jeannette Connolly,Susan Daigneault,Shirley Eberly,Janice Bausch,Lee Josephson,Rosemary Oliva,Steven R. Schwid,Anthony E. Lang,Christopher Cox,Carrie Irvine,John G. Nutt,William B. White,Sheila Oren,Ruth Levy,Eli Eyal,David Ladkani,Wayne Houck +89 more
TL;DR: Rasagiline is effective as monotherapy for patients with early PD and the 2 dosages in this trial were both effective relative to placebo.
Journal ArticleDOI
Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease
Tatiana Foroud,Sean K. Uniacke,L. Liu,Nathan Pankratz,Anja Rudolph,Cheryl Halter,Clifford W. Shults,Karen Marder,P. M. Conneally,William C. Nichols,Lawrence I. Golbe,William C. Koller,Kelly E. Lyons,Frederick J. Marshall,David Oakes,Aileen Shinaman,Eric Siemers,Joanne Wojcieszek,Joann Belden,Julie H. Carter,Richard Camicioli,Pamela Andrews,Magali Fernandez,Jean P. Hubble,Carson Reider,Ali H. Rajput,Alex Rajput,Theresa Shirley,Michael Panisset,Jean Hall,Tilak Mendis,David Grimes,Peggy Gray,Carmen Serrano Ramos,Sandra Roque,Stephen G. Reich,Becky Dunlop,Robert A. Hauser,Juan Sanchez-Ramos,Theresa A. Zesiewicz,Holly Delgado,Joseph H. Friedman,Hubert H. Fernandez,Margaret C. Lannon,Lauren Seeberger,Christopher F. O'Brien,Deborah Judd,Lawrence Elmer,Kathy Davis,Deborah Fontaine,Ronald F. Pfeiffer,Brenda Pfeiffer,Michael J. Aminoff,Mariann DiMinno,Daniel D. Truong,Mayank Pathak,Anhoa Tran,Robert L. Rodnitzky,Judith Dobson,Rajesh Pahwa,Stephanie Thomas,Danna Jennings,Kenneth Marek,Susan Mendick,Juliette Harris,William J. Weiner,Roger Kurlan,Debra Berry,Peter A. LeWitt,Maryan DeAngelis,Paul J. Tuite,Robyn Schacherer,W.R. Wayne Martin,Marguerite Wieler,Bala V. Manyam,Patricia Simpson,John M. Bertoni,Carolyn Peterson,Mark Forrest Gordon,Joanna Hamann,Joseph Jankovic,Christine Hunter,Stewart A. Factor,Sharon Evans,Anette Nieves,Julie So,Mark Stacy,Kelli Williamson,Francis O. Walker,Victoria Hunt,Un Jung Kang,Shirley Uy,Karen Bindauer,Jeannine Petit,David Simon,Lisa Scollins,Rachel Saunders Pullman,Karyn Boyer,Paul Gordon +98 more
TL;DR: Mutations in the parkin gene occur among individuals with PD with an older age at onset (≥60 years) who have a positive family history of the disease, and the clinical findings of parkin-positive individuals are remarkably similar to those without mutations.
Journal ArticleDOI
A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease
Karl Kieburtz,Bernard Ravina,Bernard Ravina,Wendy R. Galpern,Barbara C. Tilley,Kathleen M. Shannon,Caroline M. Tanner,G. Frederick Wooten,Robert W. Hamill,Jacob I. Sage,Emily Kosa,Ray L. Watts,Natividad R. Stover,Rebecca McMurray,Mark F. Lew,Connie Kawai,David Coffey,Pauline LeBlanc,Julie H. Carter,Matthew Brodsky,Pamela Andrews,Andrew Siderowf,Sue Reichwein,Lisa M. Shulman,William J. Weiner,Katharine Pabst,Jeana Jaglin,Robert A. Hauser,Theresa McClain,Holly Delgado,Oksana Suchowersky,Lorelei Derwent,Jayaraman Rao,Maureen Cook,Michael J. Aminoff,Chad W. Christine,Jessie Roth,Maureen A. Leehey,Jacci Bainbridge,G. Webster Ross,Stephanie Terashita,Carlos Singer,Marian A. Perez,Anita Blenke,Brad A. Racette,Patricia Deppen,Rodger J. Elble,Charlene Young,Tracy Stewart,Kapil D. Sethi,Buff Dill,John W. Taylor,Peggy Roberge,Richard B. Dewey,Brigid Hayward,Joseph Jankovic,Christine Hunter,Frederick Wooten,Margaret F. Keller,Danna Jennings,Tammie Kelsey,W.R. Wayne Martin,Germaine McInnes,Joanne Wojcieszek,Joann Belden,Roger L. Albin,Kristine Wernette,Joseph M. Savitt,Becky Dunlop,Rajesh Pahwa,Kelly E. Lyons,Amy Parsons,John Y. Fang,Dorothy Shearon,Andrew Feigin,Margaret Marie Cox,Charles H. Adler,Marlene Lind,Burton L. Scott,Joanne Field,Martha Nance,Susan Peterson,Richard S. Burns,Lynn Marlor,I. Van Bodis-Wollner,Elizabeth Hayes,Jay S. Schneider,Stephanie Sendek,Stephen Gollomp,Gwyn Vernon,Peter A LeWitt,Maryan DeAngelis,David Simon,Linda Paul,Jay M. Gorell,Shana Krstevska,Marilyn Flewellen,Sharon McCarthy,Ryan J. Uitti,Margaret F. Turk,James H. Bower,Susan Torgrimson,Marwan N. Sabbagh,Zoran Obradov,Jorge L. Juncos,Mary Louise Musante Weeks,Hubert H. Fernandez,Gordon H. Brown,Jordan J. Elm,Paulo Guimaraes,Peng Huang,Yuko Y. Palesch,Cornelia Kamp,Aileen Shinaman,Debbie Fraser,Alicia Brocht,Susan Bennett,Chris Weaver,Debbie Baker,Beverly Olsen,Christopher G. Goetz,Janis M. Miyasaki,Susan C. Fagan,Patrick D. Mauldin +123 more
TL;DR: Coenzyme Q10 and GPI-1485 may warrant further study in Parkinson disease, although the data are inconsistent, and additional factors should be considered in the selection of agents for Phase III studies.
Journal ArticleDOI
Significant Linkage of Parkinson Disease to Chromosome 2q36-37
Nathan Pankratz,William C. Nichols,Sean K. Uniacke,Cheryl Halter,Alice Rudolph,Cliff Shults,Cliff Shults,P. Michael Conneally,Tatiana Foroud,Lawrence I. Golbe,William C. Koller,Kelly E. Lyons,Karen Marder,Frederick J. Marshall,David Oakes,Aileen Shinaman,Eric Siemers,Joanne Wojcieszek,Joann Belden,Julie H. Carter,Richard Camicioli,Pamela Andrews,Magali Fernandez,Jean P. Hubble,Carson Reider,Ali H. Rajput,Alex Rajput,Theresa Shirley,Michel Panisset,Jean Hall,Tilak Mendis,David Grimes,Peggy Gray,Carmen Serrano Ramos,Sandra Roque,Stephen G. Reich,Becky Dunlop,Robert A. Hauser,Juan Sanchez-Ramos,Theresa A. Zesiewicz,Holly Delgado,Joseph H. Friedman,Hubert H. Fernandez,Margaret C. Lannon,Lauren Seeberger,Christopher F. O'Brien,Deborah Judd,Lawrence Elmer,Kathy Davis,Deborah Fontaine,Ronald F. Pfeiffer,Brenda Pfeiffer,Michael J. Aminoff,Mariann DiMinno,Daniel D. Truong,Mayank Pathak,Anhoa Tran,Robert L. Rodnitzky,Judith Dobson,Rajesh Pahwa,Stephanie Thomas,Danna Jennings,Kenneth Marek,Susan Mendick,Juliette Harris,William J. Weiner,Roger Kurlan,Debra Berry,Peter A. LeWitt,Maryan DeAngelis,Paul J. Tuite,Robyn Schacherer,W.R. Wayne Martin,Marguerite Wieler,Bala V. Manyam,Patricia Simpson,John M. Bertoni,Carolyn Peterson,Mark Forrest Gordon,Joanna Hamann,Joseph Jankovic,Christine Hunter,Stewart A. Factor,Sharon Evans,Anette Nieves,Julie So,Mark Stacy,Kelli Williamson,Francis O. Walker,Victoria Hunt,Un Jung Kang,Shirley Uy,Karen Blindauer,Jeannine Petit,David Simon,Lisa Scollins,Rachel Saunders Pullman,Karyn Boyar,Paul Gordon,Joan Werner +99 more
TL;DR: This work has expanded the sample to include 150 families meeting the strictest diagnostic definition of verified PD, and performs analyses using only those pedigrees with the strongest family history of PD, which strongly suggests that variation in a gene on chromosome 2q36-37 contributes to PD susceptibility.
Journal ArticleDOI
Rasagiline improves quality of life in patients with early Parkinson's disease
Kevin M. Biglan,Steven R. Schwid,Shirley Eberly,Karen Blindauer,S. Fahn,Tamar Goren,Karl Kieburtz,David Oakes,Sandra Plumb,Andrew Siderowf,Matthew B. Stern,Ira Shoulson,Denni Day,Aileen Shinaman,Mark F. Lew,Connie Kawai,Howard I. Hurtig,Mary Lloyd,Robert A. Hauser,Lisa Gauger,Robert E. Wood,Lawrence I. Golbe,Joanne Wojcieszek,Joann Belden,Andrew Feigin,Mary Lou Klimek,Barbara Shannon,William G. Ondo,Christine Hunter,Vincent Calabrese,Paul Atchinson,Frederick J. Marshall,Debra Berry,Irenita Gardiner,Janis M. Miyasaki,Luisa Del Rizzo,Tilak Mendis,Neila Mendis,Peggy Gray,Jean P. Hubble,Karen Betcher,Rajesh Pahwa,Eric Molho,Diane Brown,Sharon Evans,Lisa M. Shulman,Ali H. Rajput,Marianne Ewanishin,Mark Stacy,Kelli Williamson,John M. Bertoni,Carolyn Peterson,Paul J. Tuite,Brenda Ebbitt,Kathleen M. Shannon,Jean A. Jaglin,Caroline Taner,Kenneth Marek,Karen Stavris,Michael J. Aminoff,Mariaane DiMinno,Glenna A. Dowling,Un Jung Kang,Judy Richman,Kapil D. Sethi,W.R. Wayne Martin,Pamela King,Germaine McInnes,Charles H. Adler,Marlene Lind,Peter A. LeWitt,Maryan DeAngelis,Mark Forrest Gordon,Roberta Winnick,Robert G. Feldman,Cathi A. Thomas,Kelly M. Conn,Alicia Brocht,Chris Chadwick,Jeannette Connolly,Susan Daigneault,Janice Bausch,Lee Josephson,Rosemary Oliva,Antonio Lang,Christopher Cox,Carrie Irvine,John G. Nutt,William B. White +88 more
TL;DR: Rasagiline improved QOL compared with placebo, and this QOL improvement appears to be accounted for primarily by the symptomatic benefit of rasagILine.