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Jae Sik Yu

Researcher at Sungkyunkwan University

Publications -  65
Citations -  884

Jae Sik Yu is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Chemistry & Withania somnifera. The author has an hindex of 13, co-authored 60 publications receiving 493 citations. Previous affiliations of Jae Sik Yu include Kangwon National University.

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Bioactivity-guided isolation of ginsenosides from Korean Red Ginseng with cytotoxic activity against human lung adenocarcinoma cells.

TL;DR: Bioactivity-guided fractionation of the KRG extract revealed that its ethyl acetate–soluble fraction exerts significant cytotoxic activity against all human lung cancer cell lines tested by inducing apoptosis, providing experimental evidence for a novel biological activity of ginsenoside Rg3 againsthuman lung cancer cells.
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Therapeutic Application of Betalains: A Review

TL;DR: Findings show that betalain colorants may be a promising alternative to the synthetic dyes currently used as food additives.
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Antifungal Phenols from Woodfordia uniflora Collected in Oman

TL;DR: Phytochemical screening of the extract of W. uniflora found three new phenolic compounds, including woodfordiamycin, woodfordic acid, and rhamnetin 3-O-(6″-galloyl)-β-d-glucopyranoside, which showed antifungal activity against human fungal pathogens Cryptococcus neoformans and Candida albicans.
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Herqueilenone A, a unique rearranged benzoquinone-chromanone from the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729.

TL;DR: The study of a Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729 led to the isolation of one unprecedented benzoquinone-chromanone, herqueilenone A and two phenalenone derivatives, whose structures were determined through extensive analysis of NMR spectroscopic data and gauge-including atomic orbital (GIAO) NMR chemical shifts and ECD calculations.