James A. Katancik

TL;DR: The Human Microbiome Project Consortium reported the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome as discussed by the authors.

TL;DR: The Human Microbiome Project has analysed the largest cohort and set of distinct, clinically relevant body habitats so far, finding the diversity and abundance of each habitat’s signature microbes to vary widely even among healthy subjects, with strong niche specialization both within and among individuals.

TL;DR: The Human Microbiome Project (HMP) Consortium has established a population-scale framework which catalyzed significant development of metagenomic protocols resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomics data available to the scientific community as mentioned in this paper.

TL;DR: The study evaluated longitudinal changes in an individual's microbiome by sampling 279 participants twice and 100 individuals 3 times, yielding 11,174 primary specimens, from which 12,479 DNA samples were submitted to 4 centers for metagenomic sequencing.

TL;DR: The Diabetes and Periodontal Therapy Trial (DPTT) as mentioned in this paper was a 6-month, single-masked, multicenter, randomized clinical trial to determine if nonsurgical periodontal treatment reduces levels of glycated hemoglobin (HbA 1c ) in persons with type 2 diabetes and moderate to advanced chronic periodontitis.