J
James T. Rutka
Researcher at University of Toronto
Publications - 642
Citations - 34051
James T. Rutka is an academic researcher from University of Toronto. The author has contributed to research in topics: Epilepsy & Epilepsy surgery. The author has an hindex of 84, co-authored 618 publications receiving 30391 citations. Previous affiliations of James T. Rutka include Princeton University & Toronto Western Hospital.
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Journal ArticleDOI
Immunolocalization of Fascin, an Actin-Bundling Protein and Glial Fibrillary Acidic Protein in Human Astrocytoma Cells
TL;DR: Immunofluorescence analysis shows that fascin and GFAP are immunolocalized regionally within cells and tumors of astrocytic origin and suggest that their binding may occur during dynamic reorganization of intermediate filaments.
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Adenoviral vector-mediated gene transfer: timing of wild-type p53 gene expression in vivo and effect of tumor transduction on survival in a rat glioma brachytherapy model.
Joseph Bampoe,Jennifer Glen,Sherri-Lynn Hubbard,Bodour Salhia,Patrick Shannon,James T. Rutka,Mark Bernstein +6 more
TL;DR: The expression of wtp53 significantly improves the survival of irradiated tumor-bearing rats in the authors' model and was demonstrated to be maximum between days 1 and 3 post-vector inoculation.
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An intracranial leiomyosarcoma in a child with neurofibromatosis type 1.
TL;DR: The present case report depicts a child with NF1 in whom a tumour normally associated withNF1, a leiomyosarcoma, was diagnosed in the intracranial compartment, to be the first intrusion of its kind in the general population.
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Epithelial Cell Transforming 2 and Aurora Kinase B Modulate Formation of Stress Granule–Containing Transcripts from Diverse Cellular Pathways in Astrocytoma Cells
Adrienne Weeks,Sameer Agnihotri,Jennifer Lymer,Alan Chalil,Roberto J. Diaz,Semra Isik,Christian A. Smith,James T. Rutka +7 more
TL;DR: Evidence is provided that RNA stress granules are a novel form of epigenetic regulation in astrocytoma cells, which may be targetable by chemical inhibitors and enhance astroCytoma susceptibility to conventional therapy, such as radiation and chemotherapy.
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Low-grade astrocytoma of the tectal region as an unusual cause of knee pain: case report.
TL;DR: This case may represent the first of a primary tectal low-grade astrocytoma manifesting as a symptomatic spinal mass in a 12-year-old boy investigated for knee pain and contractures.