J
James T. Rutka
Researcher at University of Toronto
Publications - 642
Citations - 34051
James T. Rutka is an academic researcher from University of Toronto. The author has contributed to research in topics: Epilepsy & Epilepsy surgery. The author has an hindex of 84, co-authored 618 publications receiving 30391 citations. Previous affiliations of James T. Rutka include Princeton University & Toronto Western Hospital.
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Journal ArticleDOI
Management and outcomes of posterior fossa subdural hematomas in neonates.
Richard G. Perrin,James T. Rutka,James M. Drake,Hal S. Meltzer,Jonathan Hellman,Venita Jay,Harold J. Hoffman,Robin P. Humphreys +7 more
TL;DR: PFSDHs are rare but important lesions to diagnose early in the neonatal period when performed in a timely manner for signs and symptoms of brain stem dysfunction and a search for an underlying cause predisposing to a PFSDH may be revealed.
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Epileptic spasms in older pediatric patients: MEG and ictal high-frequency oscillations suggest focal-onset seizures in a subset of epileptic spasms.
Rajesh RamachandranNair,Ayako Ochi,Katsumi Imai,Mony Benifla,Tomoyuki Akiyama,Stephanie Holowka,James T. Rutka,O. Carter Snead,Hiroshi Otsubo +8 more
TL;DR: Seizure-free outcomes following resection of zone with MEGSS clusters and ictal HFOs suggested that a subset of epileptic spasms was focal-onset seizures, and unilateral clusters of MEG SSs overlapped regional IOZs in older patients with epilepticSpasms.
Journal ArticleDOI
Medulloblastoma subgroups remain stable across primary and metastatic compartments
Xin Wang,Adrian M. Dubuc,Vijay Ramaswamy,Stephen C. Mack,Deena M.A. Gendoo,Marc Remke,Xiaochong Wu,Livia Garzia,Betty Luu,Florence M.G. Cavalli,John Peacock,Borja López,Patryk Skowron,David Zagzag,David Lyden,Caitlin Hoffman,Yoon Jae Cho,Charles G. Eberhart,Tobey J. MacDonald,Xiao-Nan Li,Timothy E. Van Meter,Paul A. Northcott,Benjamin Haibe-Kains,Benjamin Haibe-Kains,Cynthia Hawkins,James T. Rutka,Eric Bouffet,Stefan M. Pfister,Andrey Korshunov,Michael D. Taylor +29 more
TL;DR: The hypothesis that medulloblastoma subgroups arise from distinct cells of origin, which are carried forward from ontogeny to oncology is supported, as are the findings of this investigation.
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The INK4A/ARF locus: role in cell cycle control and apoptosis and implications for glioma growth.
TL;DR: The frequent mutation or deletion of INK4A/ARF in human tumours as well as the occurence of tumours in the murine knockout models have identified both p16 and ARF as bona fide tumour suppressors.
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Focused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: Potential for targeting experimental brain tumors
Roberto J. Diaz,Patrick Z. McVeigh,Meaghan A. O'Reilly,Kelly Burrell,Matthew Bebenek,Christian A. Smith,Arnold B. Etame,Gelareh Zadeh,Kullervo Hynynen,Brian C. Wilson,James T. Rutka +10 more
TL;DR: N nanoparticles with SERS imaging capability can be delivered across the BBB non-invasively using TcMRgFUS and have the potential to be used as optical tracking agents at the invasive front of malignant brain tumors.