J
James T. Rutka
Researcher at University of Toronto
Publications - 642
Citations - 34051
James T. Rutka is an academic researcher from University of Toronto. The author has contributed to research in topics: Epilepsy & Epilepsy surgery. The author has an hindex of 84, co-authored 618 publications receiving 30391 citations. Previous affiliations of James T. Rutka include Princeton University & Toronto Western Hospital.
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Journal ArticleDOI
MicroRNA-144 is a circulating effector of remote ischemic preconditioning.
Jing Li,Sagar Rohailla,Nitai Gelber,James T. Rutka,Nesrin Sabah,Rachel Gladstone,Can Wei,Pingzhao Hu,Rajesh K. Kharbanda,Andrew N. Redington +9 more
TL;DR: Systemic release of microRNA 144 plays a pivotal role in the cardioprotection induced by rIPC, and the potential for plasma miR-144 as a biomarker of the effectiveness of r IPC induced by limb ischemia is assessed.
Journal ArticleDOI
Glioblastoma, a brief review of history, molecular genetics, animal models and novel therapeutic strategies.
Sameer Agnihotri,Kelly Burrell,Amparo Wolf,Sharzhad Jalali,Cynthia Hawkins,James T. Rutka,Gelareh Zadeh +6 more
TL;DR: A brief history of the disease, current molecular knowledge, lessons from animal models and emerging concepts of angiogenesis, invasion, and metabolism in GBM that may lend themselves to therapeutic targeting are summarized.
Journal ArticleDOI
Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas
Alvaro Lassaletta,Michal Zapotocky,Matthew Mistry,Vijay Ramaswamy,Marion Honnorat,Rahul Krishnatry,Ana Guerreiro Stucklin,Nataliya Zhukova,Anthony Arnoldo,Scott Ryall,Catriona Ling,Tara McKeown,Jim Loukides,Ofelia Cruz,Carmen de Torres,Cheng-Ying Ho,Roger J. Packer,Ruth G. Tatevossian,Ibrahim Qaddoumi,Julie H. Harreld,James Dalton,Jean Mulcahy-Levy,Nicholas K. Foreman,Matthias A. Karajannis,Shiyang Wang,Matija Snuderl,Amulya A. Nageswara Rao,Caterina Giannini,Mark W. Kieran,Keith L. Ligon,Maria Luisa Garrè,Paolo Nozza,Samantha Mascelli,Alessandro Raso,Sabine Mueller,Theodore Nicolaides,Karen Silva,Romain Perbet,Alexandre Vasiljevic,Cecile Faure Conter,Didier Frappaz,Sarah Leary,Courtney A. Crane,A. T. Chan,Ho Keung Ng,Zhi Feng Shi,Ying Mao,Elizabeth Finch,David D. Eisenstat,Bev Wilson,Anne Sophie Carret,Peter Hauser,David Sumerauer,Lenka Krskova,Valerie Larouche,Adam Fleming,Shayna Zelcer,Nada Jabado,James T. Rutka,Peter B. Dirks,Michael D. Taylor,Shiyi Chen,Ute Bartels,Annie Huang,David W. Ellison,Eric Bouffet,Cynthia Hawkins,Uri Tabori +67 more
TL;DR: BRAF V600E PLGG constitutes a distinct entity with poor prognosis when treated with current adjuvant therapy, and additional multivariable clinical and molecular stratification revealed that the extent of resection and CDKN2A deletion contributed independently to poor outcome in BRAF V 600E PL GG.
Journal ArticleDOI
Dynamic changes of ictal high-frequency oscillations in neocortical epilepsy: using multiple band frequency analysis.
Ayako Ochi,Hiroshi Otsubo,Elizabeth J. Donner,Irene Elliott,Ryoichi Iwata,Takanori Funaki,Yoko Akizuki,Tomoyuki Akiyama,Katsumi Imai,James T. Rutka,O. Carter Snead +10 more
TL;DR: The spatial and temporal course of ictal high‐frequency oscillations recorded by subdural EEG in children with intractable neocortical epilepsy is characterized.
Journal ArticleDOI
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
Paul A. Northcott,Thomas Hielscher,Adrian M. Dubuc,Adrian M. Dubuc,Stephen C. Mack,Stephen C. Mack,David Shih,David Shih,Marc Remke,Marc Remke,Hani Al-Halabi,Steffen Albrecht,Nada Jabado,Charles G. Eberhart,Wiesława Grajkowska,William A. Weiss,Steven C. Clifford,Eric Bouffet,James T. Rutka,James T. Rutka,Andrey Korshunov,Stefan M. Pfister,Stefan M. Pfister,Michael D. Taylor,Michael D. Taylor +24 more
TL;DR: It is demonstrated that pediatric and adult Shh-medulloblastomas are clinically, transcriptionally, genetically, and prognostically distinct.