James T. Rutka

TL;DR: Hemisp herotomy achieves good seizure control with cognitive improvement and ambulatory status post-operatively, suggesting that hemispherotomy can be offered early or late, with expectations of good seizure Control and functional outcome, even with dominant disease.

TL;DR: The biochemistry and cell biology of the each of the Cip/Kip CKIs are discussed, their role in development as evidenced by targeted mutations in mice, and their role as possible tumor suppressor genes are discussed.

TL;DR: Potential applications of nanotechnologies to neurosurgery are reviewed and how new systems may be brought closer to the operating room through modifications in nanoparticle size, overcoming the obstacles presented by the blood-brain barrier, and functionalizing nanoparticle conjugates so that they reach their target at highest concentrations possible is described.

TL;DR: The use of computerized brain-surface voltage topographic mapping to localize and identify epileptic discharges recorded on electrocorticographic (ECoG) studies in which a subdural grid was used during intracranial video electroencephalographic (IVEEG) monitoring is described.

TL;DR: Repeat hemispherotomy is an option for consideration in patients with recurrent intractable epilepsy following failed surgery for catastrophic epilepsy and advanced MRI and DTI sequences may be of value in identifying patients with residual connectivity between the affected and unaffected hemispheres.