J
Jason G. Cyster
Researcher at University of California, San Francisco
Publications - 214
Citations - 46949
Jason G. Cyster is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: B cell & Germinal center. The author has an hindex of 106, co-authored 199 publications receiving 42370 citations. Previous affiliations of Jason G. Cyster include London Research Institute & Howard Hughes Medical Institute.
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EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues
TL;DR: A role for EBI2 is established in helping control B cell position at multiple stages during the Ab response and it is suggested that E BI2 responds to a broadly distributed lipid ligand.
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Association of T-Zone Reticular Networks and Conduits with Ectopic Lymphoid Tissues in Mice and Humans
Alexander Link,Debbie L. Hardie,Stéphanie Favre,Mirjam R. Britschgi,David H. Adams,Michael Sixt,Jason G. Cyster,Christopher D. Buckley,Sanjiv A. Luther +8 more
TL;DR: TRCs and conduits are hallmarks of secondary lymphoid organs and of well-developed TLTs, in both mice and humans, and are likely to act as important scaffold and organizer cells of the T-cell–rich zone.
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A p38 MAPK-MEF2C pathway regulates B-cell proliferation
TL;DR: It is shown that MEF2C regulates proliferation in response to BCR stimulation via the p38 MAPK pathway, and p38 directly phosphorylates MEf2C via three residues in the C-terminal transactivation domain, establishing MEF 2C as a direct transcriptional effector of BCR signaling via p38MAPK.
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Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells.
TL;DR: These findings establish CRCs as a major stromal cell type in the GC DZ and suggest that CRCs support critical activities of GC B cells in the DZ niche through Cxcl12 expression and direct cell–cell interactions.
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The CDM protein DOCK2 in lymphocyte migration
Karin Reif,Jason G. Cyster +1 more
TL;DR: The role of DOCK2 in lymphocyte homing to lymphoid tissues and recent findings for other CDM family molecules that provide a basis for understanding how Dock2 might function in lymphocytes are reviewed.