J
Jeffrey G. Williams
Researcher at University of Dundee
Publications - 84
Citations - 4535
Jeffrey G. Williams is an academic researcher from University of Dundee. The author has contributed to research in topics: Dictyostelium & Gene. The author has an hindex of 34, co-authored 84 publications receiving 4403 citations. Previous affiliations of Jeffrey G. Williams include Tohoku University.
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Journal ArticleDOI
The genome of the social amoeba Dictyostelium discoideum
Ludwig Eichinger,Justin A. Pachebat,Justin A. Pachebat,Gernot Glöckner,Marie-Adèle Rajandream,Richard Sucgang,Matthew Berriman,J. Song,Rolf Olsen,Karol Szafranski,Qikai Xu,Budi Tunggal,Sarah K. Kummerfeld,Martin Madera,Bernard Anri Konfortov,Francisco Rivero,Alan T. Bankier,Rüdiger Lehmann,N. Hamlin,Robert L. Davies,Pascale Gaudet,Petra Fey,Karen E Pilcher,Guokai Chen,David L. Saunders,Erica Sodergren,P. Davis,Arnaud Kerhornou,X. Nie,Neil Hall,Christophe Anjard,Lisa Hemphill,Nathalie Bason,Patrick Farbrother,Brian A. Desany,Eric M. Just,Takahiro Morio,René Rost,Carol Churcher,J. Cooper,Stephen F. Haydock,N. van Driessche,Ann Cronin,Ian Goodhead,Donna M. Muzny,T. Mourier,Arnab Pain,Mingyang Lu,D. Harper,R. Lindsay,Heidi Hauser,Kylie R. James,M. Quiles,M. Madan Babu,Tsuneyuki Saito,Carmen Buchrieser,A. Wardroper,A. Wardroper,Marius Felder,M. Thangavelu,D. Johnson,Andrew J Knights,H. Loulseged,Karen Mungall,Karen Oliver,Claire Price,Michael A. Quail,Hideko Urushihara,Judith Hernandez,Ester Rabbinowitsch,David Steffen,Mandy Sanders,Jun Ma,Yuji Kohara,Sarah Sharp,Mark Simmonds,S. Spiegler,Adrian Tivey,Sumio Sugano,Brian White,Danielle Walker,John Woodward,Thomas Winckler,Yoshiaki Tanaka,Gad Shaulsky,Michael Schleicher,George M. Weinstock,André Rosenthal,Edward C. Cox,Rex L. Chisholm,Richard A. Gibbs,William F. Loomis,Matthias Platzer,Robert R. Kay,Jeffrey G. Williams,Paul H. Dear,Angelika A. Noegel,Bart Barrell,Adam Kuspa +98 more
TL;DR: A proteome-based phylogeny shows that the amoebozoa diverged from the animal–fungal lineage after the plant–animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral genome than have plants, animals or fungi.
Journal ArticleDOI
Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell culture shock glycoprotein of Mr 43 000
TL;DR: It is shown that SPARC is related structurally and antigenically to an Mr 43,000 glycoprotein secreted in large amounts by bovine aortic endothelial cells as part of a ‘culture shock’ response to in vitro conditions promoting their proliferation and migration.
Journal ArticleDOI
Sequence and analysis of chromosome 2 of Dictyostelium discoideum
Gernot Glöckner,Ludwig Eichinger,Karol Szafranski,Justin A. Pachebat,Alan T. Bankier,Paul H. Dear,Rüdiger Lehmann,Cornelia Baumgart,Genís Parra,Josep F. Abril,Roderic Guigó,Kai Kumpf,Budi Tunggal,Edward C. Cox,Michael A. Quail,Matthias Platzer,André Rosenthal,Angelika A. Noegel,Bart Barrell,Marie-Adèle Rajandream,Jeffrey G. Williams,Robert R. Kay,Adam Kuspa,Richard A. Gibbs,Richard Sucgang,Donna M. Muzny,Brian A. Desany,Kathy Zeng,Baoli Zhu,Pieter J. de Jong,Theodor Dingermann,Günther Gerisch,Peter Philippsen,Michael Schleicher,Stephan C. Schuster,Thomas Winckler +35 more
TL;DR: A significant number of the genes show higher similarities to genes of vertebrates than to those of other fully sequenced eukaryotes, which strengthens the view that the evolutionary position of D. discoideum is located before the branching of metazoa and fungi but after the divergence of the plant kingdom.
Journal ArticleDOI
The Dictyostelium Developmental cDNA Project: Generation and Analysis of Expressed Sequence Tags from the First-Finger Stage of Development
Takahiro Morio,Hideko Urushihara,Tamao Saito,Yoshihiro Ugawa,Hideaki Mizuno,Motonobu Yoshida,Ryuji Yoshino,Biswa Nath Mitra,Min Pi,Tomihiro Sato,Keiko Takemoto,Hiroo Yasukawa,Jeffrey G. Williams,Mineko Maeda,Ikuo Takeuchi,Hiroshi Ochiai,Yoshimasa Tanaka +16 more
TL;DR: Using size-fractionated subsets of cDNA from the first finger stage, two sets of gridded libraries were constructed for cDNA sequencing and the ESTs represent approximately 40% of genes expressed in late development, assuming that the non-redundant ESTs correspond to independent genes.
Journal ArticleDOI
Linkage of adult α- and β-globin genes in X. laevis and gene duplication by tetraploidization
Alec J. Jeffreys,Victoria Wilson,David Wood,J. Paul Simons,Robert M. Kay,Jeffrey G. Williams +5 more
TL;DR: The close linkage of α - and β-globin genes in Xenopus provides evidence that vertebrate α- andβ- globin genes evolved by tandem duplication of a single primordial globin gene.