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Jian Wang

Researcher at Guangzhou Medical University

Publications -  1831
Citations -  76717

Jian Wang is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 94, co-authored 1018 publications receiving 57783 citations. Previous affiliations of Jian Wang include Northwestern University & Johns Hopkins University School of Medicine.

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Journal ArticleDOI

Nanohydroxyapatite, Nanosilicate-Reinforced Injectable, and Biomimetic Gelatin-Methacryloyl Hydrogel for Bone Tissue Engineering.

TL;DR: Wang et al. as mentioned in this paper designed and fabricated a mesenchymal stem cell (MSC)-laden, nanohydroxyapatite (HAP), and nanosilicate (SN)-loaded bone mimetic and injectable gelatin-methacryloyl hydrogel (GelMA-HAP-SN) system for bone tissue engineering.
Reference EntryDOI

Outreach strategies for expanding health insurance coverage in children.

TL;DR: Evidence is provided that in the US providing health insurance information and application assistance, and handing out application materials in hospital emergency departments can probably both improve insurance coverage of children.
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Preclinical pharmacokinetics, disposition, and translational pharmacokinetic/pharmacodynamic modeling of savolitinib, a novel selective cMet inhibitor.

TL;DR: This research characterized its pharmacokinetics in preclinical phase, established the preclinical relationships between PK, cMet modulation and anti-tumor efficacy, and supported clinical development of savolitinib.
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A TOR2A Gene Product: Salusin-β Contributes to Attenuated Vasodilatation of Spontaneously Hypertensive Rats

TL;DR: Results indicated that enhanced salusin-β activity is involved in attenuated endothelium-dependent vasodilatation pathogenesis in SHR by activating NAD(P)H oxidase derived ROS generation and inhibiting eNOS activation and NO release.
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Remodeling of rat pulmonary artery induced by chronic smoking exposure.

TL;DR: In SD rats, smoking exposure induces pulmonary vascular remodeling and the consequences of increased SOCE include increase in TRPC1/4/6, probably via augmented BMP4 expression, which also contribute to inflammatory responses in the lung.