J
Jian Wang
Researcher at Guangzhou Medical University
Publications - 1831
Citations - 76717
Jian Wang is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 94, co-authored 1018 publications receiving 57783 citations. Previous affiliations of Jian Wang include Northwestern University & Johns Hopkins University School of Medicine.
Papers
More filters
Posted ContentDOI
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball patterned arrays
Ao Chen,Sha Liao,Mengnan Cheng,Kailong Ma,Liang Wu,Yiwei Lai,Xiaojie Qiu,Jin Yang,Wenjiao Li,Jiangshan Xu,Shijie Hao,Xin Wang,Huifang Lu,Xi Chen,Xing Liu,Xin Huang,Feng Lin,Zhao Li,Yan Hong,Defeng Fu,Yujia Jiang,Jian Peng,Shuai Liu,Mengzhe Shen,Chuanyu Liu,Quanshui Li,Yue Yuan,Huiwen Zheng,Zhifeng Wang,Zhaohui Wang,Haitao Xiang,Lei Han,Baoming Qin,Pengcheng Guo,Pura Muñoz Cánoves,Jean Paul Thiery,Qing-Feng Wu,Fuxiang Zhao,Mei Li,Haoyan Kuang,Junhou Hui,Ou Wang,Haorong Lu,Bo Wang,Shiping Liu,Ming Ni,Wenwei Zhang,Feng Mu,Ye Yin,Huanming Yang,Michael Lisby,Richard J. Cornall,Jan Mulder,Jan Mulder,Mathias Uhlén,Mathias Uhlén,Miguel A. Esteban,Yuxiang Li,Longqi Liu,Xun Xu,Jian Wang +60 more
TL;DR: In this paper, the authors combined DNA nanoball (DNB) patterned arrays and tissue RNA capture to create SpaTial Enhanced REsolution Omics-sequencing (Stereo-seq), which allows transcriptomic profiling of large histological sections with high resolution and sensitivity.
Journal ArticleDOI
Exposure to nitrogen dioxide and chronic obstructive pulmonary disease (COPD) in adults: a systematic review and meta-analysis
TL;DR: Overall, this study reported consistent evidence of the potential positive association between NO2 and COPD risk and observed the effect of NO2 on COPD mortality with a large majority in lag0.
Journal ArticleDOI
A novel affordable reagent for room temperature storage and transport of fecal samples for metagenomic analyses.
Mo Han,Lilan Hao,Yuxiang Lin,Fang Li,Jian Wang,Huanming Yang,Liang Xiao,Karsten Kristiansen,Huijue Jia,Junhua Li +9 more
TL;DR: A novel chemical stabilizer that allows cost-effective transportation and storage at room temperature for several days with preservation of bacterial composition is described and will facilitate sample collection even in remote area and also enable transport via normal commercial transportation routes.
Journal ArticleDOI
Sodium tanshinone IIA sulfonate inhibits canonical transient receptor potential expression in pulmonary arterial smooth muscle from pulmonary hypertensive rats.
Jian Wang,Qian Jiang,Limei Wan,Kai Yang,Kai Yang,Yi Zhang,Yi Zhang,Yuqin Chen,Elizabeth Wenqian Wang,Ning Lai,Ning Lai,Lei Zhao,Hua Jiang,Yueqian Sun,Nanshan Zhong,Pixin Ran,Wenju Lu +16 more
TL;DR: It is indicated that STS prevents pulmonary arterial hypertension development likely by inhibiting TRPC1 and TRPC6 expression, resulting in normalized basal [Ca(2+)](i) and attenuated proliferation and migration of PASMCs.
Journal ArticleDOI
Tanshinone IIA sulfonate protects against cigarette smoke-induced COPD and down-regulation of CFTR in mice.
Defu Li,Jian Wang,Dejun Sun,Xuefang Gong,Hua Jiang,Jiaze Shu,Ziyi Wang,Zhen Long,Yiguan Chen,Zili Zhang,Liang Yuan,Ruijuan Guan,Xue Liang,Ziying Li,Hongwei Yao,Nanshan Zhong,Wenju Lu +16 more
TL;DR: It is found that STS inhalation significantly attenuated lung function decline, airspace enlargement, mucus production, bronchial collagen deposition, inflammatory responses and oxidative stress caused by cigarette smoke and lipopolysaccharide exposures in mice.