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Jinchao Yu

Researcher at Université Paris-Saclay

Publications -  17
Citations -  603

Jinchao Yu is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Macromolecular docking & Docking (molecular). The author has an hindex of 11, co-authored 15 publications receiving 462 citations. Previous affiliations of Jinchao Yu include University of Paris-Sud & Commissariat à l'énergie atomique et aux énergies alternatives.

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Prediction of homoprotein and heteroprotein complexes by protein docking and template-based modeling: A CASP-CAPRI experiment.

Marc F. Lensink, +104 more
- 01 Jun 2016 - 
TL;DR: Results show that the prediction of homodimer assemblies by homology modeling techniques and docking calculations is quite successful for targets featuring large enough subunit interfaces to represent stable associations, and that docking procedures tend to perform better than standard homology modeled techniques.
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InterEvDock: a docking server to predict the structure of protein-protein interactions using evolutionary information.

TL;DR: In 91% of all complexes tested in the benchmark, at least one residue out of the 10 predicted is involved in the interface, providing useful guidelines for mutagenesis, making InterEvDock a unique and efficient tool to explore structural interactomes under an evolutionary perspective.
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Next-generation drug repurposing using human genetics and network biology.

TL;DR: Progress and perspectives in combining human genetics, especially genome-wide association studies, with network biology to drive drug repurposing for rare and common diseases with monogenic or polygenic etiologies are reviewed.
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InterEvDock2: an expanded server for protein docking using evolutionary and biological information from homology models and multimeric inputs

TL;DR: The InterEvDock2 pipeline was benchmarked on 812 complexes for which unbound homology models of the two partners and co-evolutionary information are available in the PPI4DOCK database and identified a correct model among the top 10 consensus in 29% of cases and at least one correct interface residue among 10 predicted in 91% of these cases.