E
Eugene Berezikov
Researcher at University Medical Center Groningen
Publications - 132
Citations - 15916
Eugene Berezikov is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Macrostomum lignano & Gene. The author has an hindex of 49, co-authored 128 publications receiving 14662 citations. Previous affiliations of Eugene Berezikov include Royal Netherlands Academy of Arts and Sciences & Skolkovo Institute of Science and Technology.
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Journal ArticleDOI
MicroRNA Expression in Zebrafish Embryonic Development
Erno Wienholds,Wigard P. Kloosterman,Eric A. Miska,Ezequiel Alvarez-Saavedra,Eugene Berezikov,Ewart de Bruijn,H. Robert Horvitz,Sakari Kauppinen,Ronald H.A. Plasterk +8 more
TL;DR: Most miRNAs were expressed in a highly tissue-specific manner during segmentation and later stages, but not early in development, which suggests that their role is not in tissue fate establishment but in differentiation or maintenance of tissue identity.
Journal ArticleDOI
Phylogenetic Shadowing and Computational Identification of Human microRNA Genes
Eugene Berezikov,Victor Guryev,Jose van de Belt,Erno Wienholds,Ronald H.A. Plasterk,Edwin Cuppen +5 more
TL;DR: In this paper, the authors sequenced 122 miRNAs in 10 primate species to reveal conservation characteristics of miRNA genes, including stems of miRN hairpins and increased variation in loop sequences.
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Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE
Sushmita Roy,Jason Ernst,Peter V. Kharchenko,Pouya Kheradpour,Nicolas Nègre,Matthew L. Eaton,Jane M. Landolin,Christopher A. Bristow,Lijia Ma,Michael F. Lin,Stefan Washietl,Bradley I. Arshinoff,Ferhat Ay,Patrick E. Meyer,Nicolas Robine,Nicole L. Washington,Luisa Di Stefano,Eugene Berezikov,Christopher D. Brown,Rogerio Candeias,Joseph W. Carlson,Adrian Carr,Irwin Jungreis,Daniel Marbach,Rachel Sealfon,Michael Y. Tolstorukov,Sebastian Will,Artyom A. Alekseyenko,Carlo G. Artieri,Benjamin W. Booth,Angela N. Brooks,Qi Dai,Carrie A. Davis,Michael O. Duff,X. Feng,Andrey A. Gorchakov,Tingting Gu,Jorja G. Henikoff,Philipp Kapranov,Renhua Li,Heather K. MacAlpine,John H. Malone,Aki Minoda,Jared T. Nordman,Katsutomo Okamura,Marc D. Perry,Sara K. Powell,Nicole C. Riddle,Akiko Sakai,Anastasia Samsonova,Jeremy E. Sandler,Yuri B. Schwartz,Noa Sher,Rebecca Spokony,David Sturgill,Marijke J. van Baren,Kenneth H. Wan,Li Yang,Charles Yu,Elise A. Feingold,Peter J. Good,Mark S. Guyer,Rebecca F. Lowdon,Kami Ahmad,Justen Andrews,Bonnie Berger,Steven E. Brenner,Michael R. Brent,Lucy Cherbas,Sarah C. R. Elgin,Thomas R. Gingeras,Robert L. Grossman,Roger A. Hoskins,Thomas C. Kaufman,W. J. Kent,Mitzi I. Kuroda,Terry L. Orr-Weaver,Norbert Perrimon,Vincenzo Pirrotta,James W. Posakony,Bing Ren,Steven Russell,Peter Cherbas,Brenton R. Graveley,Suzanna E. Lewis,Gos Micklem,Brian Oliver,Peter J. Park,Susan E. Celniker,Steven Henikoff,Gary H. Karpen,Eric C. Lai,David M. MacAlpine,Lincoln Stein,Kevin P. White,Manolis Kellis +95 more
TL;DR: The Drosophila Encyclopedia of DNA Elements (modENCODE) project as mentioned in this paper has been used to map transcripts, histone modifications, chromosomal proteins, transcription factors, replication proteins and intermediates, and nucleosome properties across a developmental time course and in multiple cell lines.
Journal ArticleDOI
A Role for Piwi and piRNAs in Germ Cell Maintenance and Transposon Silencing in Zebrafish
Saskia Houwing,Leonie M. Kamminga,Eugene Berezikov,Daniela Cronembold,Angélique Girard,Hans van den Elst,Dmitri V. Filippov,Heiko Blaser,Erez Raz,Cecilia B. Moens,Ronald H.A. Plasterk,Gregory J. Hannon,Bruce W. Draper,René F. Ketting +13 more
TL;DR: It is demonstrated that zebrafish Piwi (Ziwi) is expressed in both the male and the female gonad and is a component of a germline-specifying structure called nuage, implicating a role for piRNAs in the silencing of repetitive elements in vertebrates.
Journal ArticleDOI
Mammalian mirtron genes.
TL;DR: The existence of well-conserved mammalian mirtrons indicates their relatively ancient incorporation into endogenous regulatory pathways, and it is hypothesized that different animals may have independently evolved the capacity for this hybrid small RNA pathway.