Judit P. Vigh

TL;DR: In this paper, the authors describe setups, electrodes, and instruments to measure electrical resistance across brain microvessels and culture models of the BBB, as well as critically assess the influence of often neglected physical and technical parameters such as temperature, viscosity, current density generated by different electrode types, surface size, circumference, and porosity of the culture insert membrane.

TL;DR: In this article, a microfluidic lab-on-a-chip (LOC) device was used to study fluid flow in the regulation of endothelial, BBB and glycocalyx-related genes and surface charge.

TL;DR: The Symposium program covered all areas of blood–brain barriers research with the focus on the latest developments in neurodegenerative diseases, membrane receptors and transporters, transcytosis regulators, epigenetic and transcriptional regulators, metabolic and nutrition regulation, in vivo and in vitro brain barriers models as well as the role of junctional complexes.

TL;DR: It is found that spike protein crossed the human brain endothelial cell barrier effectively and was found in a lower amount for the intestinal barrier cell layer.

TL;DR: It is concluded that in chronic hypertriglyceridemic APOB-100 transgenic mice both functional and morphological cerebrovascular pathology can be observed, and this animal model could be a useful tool to study the link between cerebroVascular pathology and neurodegeneration.