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Jordi Garcia-Fernàndez

Researcher at University of Barcelona

Publications -  112
Citations -  9151

Jordi Garcia-Fernàndez is an academic researcher from University of Barcelona. The author has contributed to research in topics: Hox gene & Cephalochordate. The author has an hindex of 42, co-authored 112 publications receiving 8546 citations. Previous affiliations of Jordi Garcia-Fernàndez include University of St Andrews & University of Oxford.

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The amphioxus genome and the evolution of the chordate karyotype

TL;DR: Whole-genome comparisons illuminate the murky relationships among the three chordate groups (tunicates, lancelets and vertebrates), and allow not only reconstruction of the gene complement of the last common chordate ancestor but also partial reconstruction of its genomic organization.
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Gene duplications and the origins of vertebrate development

TL;DR: From amphioxus and vertebrate homeobox gene expression patterns, it is suggested that there are multiple routes by which new genes arising from gene duplication acquire new functions and permit the evolution of developmental innovations.
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Archetypal organization of the amphioxus Hox gene cluster.

TL;DR: The amphioxus genome has only one Hox gene cluster, and contains homologues of at least the first ten paralogous groups of vertebrate Hox genes in a collinear array, compatible with that inferred for a direct ancestor of the vertebrates.
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The amphioxus genome illuminates vertebrate origins and cephalochordate biology

Linda Z. Holland, +71 more
- 01 Jul 2008 - 
TL;DR: The results indicate that the amphioxus genome is elemental to an understanding of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates.
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The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster

TL;DR: It is proposed that the origin of distinct Hox and ParaHox genes by gene-cluster duplication facilitated an increase in body complexity during the Cambrian explosion and it is argued that this ‘ParaHox’ gene cluster is an ancient paralogue of the Hox gene cluster.