Showing papers by "Jun Ma published in 2022"
TL;DR: In this article, the authors proposed a simple and efficient approach to strengthen the oxidation capacity of heat-activated peroxymonosulfate (PMS) and highlighted the superiority of PDS in thermolysis under alkaline conditions.
57 citations
TL;DR: In this paper , a facile approach to develop "oil-diode" Janus membranes with the special wettable structure for fast oil refining is provided, and the manufactured membranes exhibit extra high oil intrusion pressure up to 12 kPa and present high permeance of about 2993 L m-2 h-1 bar-1 in separating stable water-in-oil emulsion containing surfactant and separation efficiency up to 99.6%, thereby showing promising potential in oil recovery and refining.
Abstract: Oil leakage is a global environmental issue and happens frequently, resulting in a waste of oil resources and even threatening the safety of marine creatures and humans. Because of unidirectional oil transportation performance, "oil-diode" Janus membranes have attracted lots of attention for oil/water separation. However, the hydrophobic side of traditional "oil-diode" Janus membrane is completely hydrophobic, resulting in an easy permeation of oil, which hampers light oil recycling. Herein, we provide a facile approach to develop "oil-diode" Janus membranes with the special wettable structure for fast oil refining. The material characteristics and surface wettability of the membranes that generate superimposed efforts are vital to fabricate "oil-diode" Janus membranes. Interestingly, the manufactured membranes exhibit extra-high oil intrusion pressure up to 12 kPa and present high permeance of about 2993 L m-2 h-1 bar-1 in separating stable water-in-oil emulsion containing surfactant and separation efficiency up to 99.6%, thereby showing promising potential in oil recovery and refining.
47 citations
TL;DR: It is shown that Wilms' tumor 1-associating protein (WTAP) expression was apparently upregulated in NPC, and increased WTAP was associated with poor prognosis, and WTAP-mediated DIAPH1-AS1 m6A methylation is required for NPC tumorigenesis and metastasis.
42 citations
TL;DR: In this paper, the authors presented a relatively comprehensive summary on this topic, comparing the homogeneous hydrogen peroxide-based and persulfates-based AOPs initiated by Cu(II), with an emphasis on the reaction mechanisms.
42 citations
TL;DR: The authors showed that CG methylation and non-CG methylation are required for a plethora of biological processes, including pavement cell shape, endoreduplication, cell death, flowering, trichome morphology, vasculature and meristem development, and root cell fate determination.
Abstract: A contribution of DNA methylation to defense against invading nucleic acids and maintenance of genome integrity is uncontested; however, our understanding of the extent of involvement of this epigenetic mark in genome-wide gene regulation and plant developmental control is incomplete. Here, we knock out all five known DNA methyltransferases in Arabidopsis, generating DNA methylation-free plants. This quintuple mutant exhibits a suite of developmental defects, unequivocally demonstrating that DNA methylation is essential for multiple aspects of plant development. We show that CG methylation and non-CG methylation are required for a plethora of biological processes, including pavement cell shape, endoreduplication, cell death, flowering, trichome morphology, vasculature and meristem development, and root cell fate determination. Moreover, we find that DNA methylation has a strong dose-dependent effect on gene expression and repression of transposable elements. Taken together, our results demonstrate that DNA methylation is dispensable for Arabidopsis survival but essential for the proper regulation of multiple biological processes.
40 citations
TL;DR: In this paper , the role of advanced oxidation processes (AOPs) in sludge dewatering to improve sludge treatment, disposal and environmental protection has attracted much interest due to the difficulties arising in extracellular polymeric substances (EPS) degradation during the sludge degradation process.
Abstract: Applying advanced oxidation processes (AOPs) in sludge dewatering to improve sludge treatment, disposal and environmental protection has attracted much interest due to the difficulties arising in extracellular polymeric substances (EPS) degradation during the sludge dewatering process. Oxidants can produce different types of free radicals and exert specific oxidation effects through different action mechanisms on water saturated sludge. This plays an important role in sludge dewatering, sludge minimization and removal of different types of micropollutants and/or their transformation. The current review critically evaluates the role of AOP in improving the efficiency of sludge dewatering. Characteristics of advanced oxidation methods applied to sludge dewatering are systematically illustrated through different mechanisms using free radical reactions and various sludge dewatering conditions. Factors which impact on influencing the minimization of sludge and removals of typical micropollutants during the sludge conditioning process are also analyzed. Finally, applications of advanced oxidation methods in the future are proposed based on a technoeconomic analyses of dewatering efficiency and operation cost. This review provides theoretical support regarding the application of advanced oxidation processes in sludge dewatering and avenues for practical engineering. In the current review, it is determined that the efficiency of AOP for the improvement of sludge dewatering, micropollutants removal and sludge minimization in the treatment and disposal of sludge have been fully investigated. Unfortunately, there is still lack of comparing the ability of different free radicals on published review.
39 citations
TL;DR: In this article , a facile layer-by-layer assembly method was designed to construct a series of de novo positively-charged tannic acid/polyethyleneimine (TA/PEI) membranes containing a negatively-charged support membrane and a TA/PEIs selective layer.
37 citations
TL;DR: In this article, a review mainly introduces the varied classes of electrolyte functional additives and their working mechanism for interfacial engineering of Ni-rich cathodes, and the key favorable species for stabilizing CEI layer are summarized.
33 citations
TL;DR: In this paper , an open-label, non-inferiority, randomised, controlled, phase 3 trial was conducted at three Chinese medical centres to address whether elective ipsilateral upper-neck irradiation (UNI) sparing the uninvolved lower neck provides similar regional relapse-free survival compared with standard whole-neck ionization (WNI) in patients with nasopharyngeal carcinoma.
Abstract: The aim of this trial was to address whether elective ipsilateral upper-neck irradiation (UNI) sparing the uninvolved lower neck provides similar regional relapse-free survival compared with standard whole-neck irradiation (WNI) in patients with nasopharyngeal carcinoma.This open-label, non-inferiority, randomised, controlled, phase 3 trial was done at three Chinese medical centres. Patients aged 18-65 years with untreated, non-keratinising, non-distant metastatic (M0) nasopharyngeal carcinoma; with N0-N1 disease (according to International Union Against Cancer-American Joint Committee on Cancer TNM classification, seventh edition); and a Karnofsky performance status score of 70 or higher were randomly assigned (1:1) to receive elective UNI or WNI of the uninvolved neck. Total radiation doses of 70 Gy (for the primary tumour volume and the enlarged retropharyngeal nodes), 66-70 Gy (for the involved cervical lymph nodes), 60-62 Gy (for the high-risk target volume), and 54-56 Gy (for the low-risk target volume) were administered in 30-33 fractions, five fractions per week. Patients with stage II-IVA disease were recommended to receive combined intravenous cisplatin-based chemotherapy (either induction chemotherapy followed by concurrent chemoradiotherapy or concurrent chemoradiotherapy alone). Randomisation was done centrally by the Clinical Trials Centre of Sun Yat-sen University Cancer Centre by means of a computer-generated random number code with a block size of four. Patients were stratified according to treatment centre and nodal status. Investigators and patients were not masked to treatment allocation. The primary endpoint was regional relapse-free survival in the intention-to-treat population. Non-inferiority was indicated if the upper limit of the 95% CI of the difference in 3-year regional relapse-free survival between the UNI and WNI groups was within 8%. Adverse events were analysed in the safety population (defined as all patients who commenced the randomly assigned treatment). This study is registered with ClinicalTrials.gov, NCT02642107, and is closed.Between Jan 22, 2016, and May 23, 2018, 446 patients from 469 screened were randomly assigned to receive UNI (n=224) or WNI (n=222). Median follow-up was 53 months (IQR 46-59). 3-year regional relapse-free survival was similar in the UNI and WNI groups (97·7% [95% CI 95·7-99·7] in the UNI group vs 96·3% [93·8-98·8] in the WNI group; difference -1·4% [95% CI -4·6 to 1·8]; pnon-inferiority<0·0001). Although acute radiation-related toxic effects were similar between the groups, the incidence of late toxicity was lower in the UNI group than in the WNI group, including any-grade hypothyroidism (66 [30%] of 222 patients vs 87 [39%] of 221), skin toxicity (32 [14%] vs 55 [25%]), dysphagia (38 [17%] vs 71 [32%]), and neck tissue damage (50 [23%] vs 88 [40%]). No patients died during treatment. After treatment, one patient in the WNI group died from a non-cancer-related cause (dermatomyositis).Elective UNI of the uninvolved neck provides similar regional control and results in less radiation toxicity compared with standard WNI in patients with N0-N1 nasopharyngeal carcinoma.Sun Yat-sen University Clinical Research 5010 Program, the Natural Science Foundation of Guangdong Province, and the Overseas Expertise Introduction Project for Discipline Innovation.For the Chinese translation of the abstract see Supplementary Materials section.
30 citations
TL;DR: PAA was found to be effective for the inactivation of fungal spores, but was less effective than several traditional disinfectants under the same condition, and the regrowth offungal spores after disinfection with PAA was also evaluated.
28 citations
TL;DR: In this article , the electrode aeration (EA) and hydroxylamine sulfate (HA) were coupled to improve H2O2 generation and Fe3+/Fe2+ cycle simultaneously for enhancing Electro-Fenton performance.
TL;DR: Among patients with low-risk NPC, treatment with IMRT alone resulted in 3-year failure-free survival that was not inferior to concurrent chemoradiotherapy, and the IMRT-alone group had significantly better QOL scores during radiotherapy including the domains of global health status, social functioning, fatigue, nausea and vomiting, pain, insomnia, appetite loss, and constipation.
Abstract: Importance
Concurrent chemoradiotherapy has been the standard treatment for stage II nasopharyngeal carcinoma (NPC) based on data using 2-dimensional conventional radiotherapy. There is limited evidence for the role of chemotherapy with use of intensity-modulated radiation therapy (IMRT).
Objective
To assess whether concurrent chemotherapy can be safely omitted for patients with low-risk stage II/T3N0 NPC treated with IMRT.
Design, Setting, and Participants
This multicenter, open-label, randomized, phase 3, noninferiority clinical trial was conducted at 5 Chinese hospitals, including 341 adult patients with low-risk NPC, defined as stage II/T3N0M0 without adverse features (all nodes <3 cm, no level IV/Vb nodes; no extranodal extension; Epstein-Barr virus DNA <4000 copies/mL), with enrollment between November 2015 and August 2020. The final date of follow-up was March 15, 2022.
Interventions
Patients were randomly assigned to receive IMRT alone (n = 172) or concurrent chemoradiotherapy (IMRT with cisplatin, 100 mg/m2 every 3 weeks for 3 cycles [n = 169]).
Main Outcomes and Measures
The primary end point was 3-year failure-free survival (time from randomization to any disease relapse or death), with a noninferiority margin of 10%. Secondary end points comprised overall survival, locoregional relapse-free survival, distant metastasis-free survival, adverse events, and health-related quality of life (QOL) measured by the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30; range, 0-100 points; minimum clinically important difference ≥10 for physical function, symptom control, or health-related QOL; higher score indicates better functioning and global health status or worse symptoms).
Results
Among 341 randomized patients (mean [SD] age, 48 [10] years; 30% women), 334 (98.0%) completed the trial. Median follow-up was 46 months (IQR, 34-58). Three-year failure-free survival was 90.5% for the IMRT-alone group vs 91.9% for the concurrent chemoradiotherapy group (difference, -1.4%; 1-sided 95% CI, -7.4% to ∞; P value for noninferiority, <.001). No significant differences were observed between groups in overall survival, locoregional relapse, or distant metastasis. The IMRT-alone group experienced a significantly lower incidence of grade 3 to 4 adverse events (17% vs 46%; difference, -29% [95% CI, -39% to -20%]), including hematologic toxicities (leukopenia, neutropenia) and nonhematologic toxicities (nausea, vomiting, anorexia, weight loss, mucositis). The IMRT-alone group had significantly better QOL scores during radiotherapy including the domains of global health status, social functioning, fatigue, nausea and vomiting, pain, insomnia, appetite loss, and constipation.
Conclusions and Relevance
Among patients with low-risk NPC, treatment with IMRT alone resulted in 3-year failure-free survival that was not inferior to concurrent chemoradiotherapy.
Trial Registration
ClinicalTrials.gov Identifier: NCT02633202.
TL;DR: In this article , a novel nanocomposite hydrogel-coated membrane was designed by one-step dip-coating of tannic acid (TA)/sodium alginate (SA)/3-aminopropyltriethoxysilane (APTES) co-depositing strategy, which combines the robust adhesion of TA, the hierarchical architecture induced by APTES and the strong hydration ability of SA.
TL;DR: Wang et al. as mentioned in this paper studied the correlation and coordination between chlorine resistance mechanism and antibiotic resistance mechanism of chlorine-resistant bacteria and put forward a strategy to control the growth of CRB by controlling the concentration of biodegradable dissolved organic carbon (BDOC) in the front section of the water network.
Abstract: The extensive use of antibiotics leads to the occurrences of antibiotic resistance genes (ARGs) in aquatic environment. As an emerging environmental pollutant, its pollution in aquatic environment has aroused widespread concern. However, the residues of antibiotics and antibiotic resistance genes in drinking water distribution system were barely reported up to now. Here, we studied the correlation and coordination between chlorine resistance mechanism and antibiotic resistance mechanism of chlorine-resistant bacteria. Antibiotics induce the resistance of chlorine-resistant bacteria (CRB) to NaClO, so that low-dose disinfectants can not inactivate CRB. We put forward a strategy to control the growth of CRB by controlling the concentration of biodegradable dissolved organic carbon (BDOC) in the front section of the water network. Moreover, We screened two strains of chlorine-resistant bacteria with different antibiotic resistance after mixed culture, the results showed that antibiotic resistance could spread horizontally among different kinds of bacteria. Then, the non-pathogenic bacteria can be used as a carrier, causing the pathogen to become resistant to antibiotic, and ultimately pose harm to human health. Generally, the antibiotic, antibiotic resistant genes, and the chlorine disinfectants added in water treatment plants will interact with bacteria in the water supply pipe network, which causes pollution to drinking water.
TL;DR: In this article , the authors investigated how humic acid (HA) influenced gypsum-induced membrane scaling and wetting during membrane distillation (MD) for hypersaline water/wastewater treatment.
Abstract: Membrane scaling and wetting severely hinder practical applications of membrane distillation (MD) for hypersaline water/wastewater treatment. In this regard, the effects of feedwater constituents are still not well understood. Herein, we investigated how humic acid (HA) influenced gypsum-induced membrane scaling and wetting during MD desalination. At low concentrations (5-20 mg L-1), HA notably mitigated membrane scaling and wetting. The morphological characterization of scaled membranes revealed that the antiwetting behavior could be ascribed to the formation of a compact and protective gypsum/HA scale layer, which blocked the flow channel of scaling ions and suppressed the intrusion of scale particles into membrane pores. Based on the comprehensive analysis of the scaling process, the formation of the scale layer was related to the heterogeneous crystallization of gypsum on the membrane surface. Moreover, deprotonated HA interfered with the heterogeneous crystallization process by inhibiting the formation of gypsum nuclei and altering the orientation of crystal growth, thus delaying membrane scaling and altering the morphology of the scale layer. Thermodynamic and kinetic analyses further demonstrated the mitigation mechanism of HA. Furthermore, improved fouling reversibility and antiwetting ability in synthetic seawater treatment endowed by HA were observed. This study provides new insight into the roles played by the organic constituents of water/wastewater during membrane desalination, providing a valuable reference for developing novel strategies to improve the performance of MD.
TL;DR: The results suggest that the intratumoral bacterial load may be a reliable prognostic indicator for patients with NPC.
Abstract: Key Points Question Is there characteristic microbiota in nasopharyngeal carcinoma (NPC) tissues and, if so, is it associated with prognosis? Findings In this multicenter cohort study including 802 patients with NPC, we confirmed the existence of microbiota within NPC tissues, which mainly originated from the nasopharynx. Intratumoral bacterial load was associated with poor survival in patients with NPC and was negatively associated with T-lymphocyte infiltration. Meaning The results suggest that the intratumoral bacterial load may be a reliable prognostic indicator for patients with NPC.
TL;DR: In this paper , the authors summarize the timely references and insights for the recent advances in metal-organic frameworks (MOFs) that are used in advanced oxidation progresses (AOP) for organic contaminants degradation in water treatment.
TL;DR: In this paper , the deubiquitinase USP44 is hypermethylated in nasopharyngeal carcinoma (NPC), which results in its downregulation.
Abstract: Radiotherapy is the primary treatment for patients with nasopharyngeal carcinoma (NPC), and approximately 20% of patients experience treatment failure due to tumour radioresistance. However, the exact regulatory mechanism remains poorly understood. Here, we show that the deubiquitinase USP44 is hypermethylated in NPC, which results in its downregulation. USP44 enhances the sensitivity of NPC cells to radiotherapy in vitro and in vivo. USP44 recruits and stabilizes the E3 ubiquitin ligase TRIM25 by removing its K48-linked polyubiquitin chains at Lys439, which further facilitates the degradation of Ku80 and inhibits its recruitment to DNA double-strand breaks (DSBs), thus enhancing DNA damage and inhibiting DNA repair via non-homologous end joining (NHEJ). Knockout of TRIM25 reverses the radiotherapy sensitization effect of USP44. Clinically, low expression of USP44 indicates a poor prognosis and facilitates tumour relapse in NPC patients. This study suggests the USP44-TRIM25-Ku80 axis provides potential therapeutic targets for NPC patients.
TL;DR: In this paper , the deubiquitinase USP44 is hypermethylated in nasopharyngeal carcinoma (NPC), which results in its downregulation.
Abstract: Radiotherapy is the primary treatment for patients with nasopharyngeal carcinoma (NPC), and approximately 20% of patients experience treatment failure due to tumour radioresistance. However, the exact regulatory mechanism remains poorly understood. Here, we show that the deubiquitinase USP44 is hypermethylated in NPC, which results in its downregulation. USP44 enhances the sensitivity of NPC cells to radiotherapy in vitro and in vivo. USP44 recruits and stabilizes the E3 ubiquitin ligase TRIM25 by removing its K48-linked polyubiquitin chains at Lys439, which further facilitates the degradation of Ku80 and inhibits its recruitment to DNA double-strand breaks (DSBs), thus enhancing DNA damage and inhibiting DNA repair via non-homologous end joining (NHEJ). Knockout of TRIM25 reverses the radiotherapy sensitization effect of USP44. Clinically, low expression of USP44 indicates a poor prognosis and facilitates tumour relapse in NPC patients. This study suggests the USP44-TRIM25-Ku80 axis provides potential therapeutic targets for NPC patients.
TL;DR: In conclusion, induction chemotherapy before concurrent chemoradiotherapy improved OS significantly in patients with locally advanced nasopharyngeal carcinoma, without increasing the risk of late toxicities.
Abstract: Clinical trials frequently include multiple end points that mature at different times. The initial report, typically on the based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been reported. We previously reported significantly improved failure-free survival using gemcitabine plus cisplatin induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma. Here, we present the final overall survival (OS) analysis. In this multicenter, randomized trial, patients were assigned to be treated with concurrent chemoradiotherapy alone (standard therapy, n = 238) or gemcitabine and cisplatin induction chemotherapy before concurrent chemoradiotherapy (n = 242). With a median follow-up of 69.8 months, the induction chemotherapy group had a significantly higher 5-year OS (87.9% v 78.8%, hazard ratio, 0.51 [95% CI 0.34 to 0.78]; P = .001) and a comparable risk of late toxicities (≥ grade 3, 11.3% v 11.4%). Notably, the depth of the tumor response to induction chemotherapy correlated significantly and positively with survival (complete response v partial response v stable/progressive disease, 5-year OS, 100% v 88.4% v 61.5%, P = .005). Besides, patients with a low pretreatment cell-free Epstein-Barr virus DNA load (< 4,000 copies/mL) might not benefit from induction chemotherapy (5-year OS, 90.6% v 91.4%, P = .77). In conclusion, induction chemotherapy before concurrent chemoradiotherapy improved OS significantly in patients with locally advanced nasopharyngeal carcinoma, without increasing the risk of late toxicities. Tumor response to induction chemotherapy and pretreatment cell-free Epstein-Barr virus DNA might be useful to guide individualized treatment.
TL;DR: Wang et al. as mentioned in this paper introduced an immune-associated nine-lncRNA signature for predicting distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC).
Abstract: Increasing evidence has revealed the roles of long noncoding RNAs (lncRNAs) as tumor biomarkers. Here, we introduce an immune-associated nine-lncRNA signature for predicting distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC). The nine lncRNAs are identified through microarray profiling, followed by RT-qPCR validation and selection using a machine learning method in the training cohort (n = 177). This nine-lncRNA signature classifies patients into high and low risk groups, which have significantly different distant metastasis-free survival. Validations in the Guangzhou internal (n = 177) and Guilin external (n = 150) cohorts yield similar results, confirming that the signature is an independent risk factor for distant metastasis and outperforms anatomy-based metrics in identifying patients with high metastatic risk. Integrative analyses show that this nine-lncRNA signature correlates with immune activity and lymphocyte infiltration, which is validated by digital pathology. Our results suggest that the immune-associated nine-lncRNA signature can serve as a promising biomarker for metastasis prediction in LA-NPC.
TL;DR: In this article, the authors designed vacancy-containing P2-Na2/3[Zn1/9Mn7/9□ 1/9]O2 (NZMO-Vac) and vacancy-free P 2-Na 2/3 [Zn 2/9 Mn7 /9] O2 (NSMO/O2) to clarify how the vacancies tailor the spinning states of the Mn3+ ions and benefit the structural stability.
TL;DR: Wang et al. as mentioned in this paper introduced an immune-associated nine-lncRNA signature for predicting distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC).
Abstract: Increasing evidence has revealed the roles of long noncoding RNAs (lncRNAs) as tumor biomarkers. Here, we introduce an immune-associated nine-lncRNA signature for predicting distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC). The nine lncRNAs are identified through microarray profiling, followed by RT-qPCR validation and selection using a machine learning method in the training cohort (n = 177). This nine-lncRNA signature classifies patients into high and low risk groups, which have significantly different distant metastasis-free survival. Validations in the Guangzhou internal (n = 177) and Guilin external (n = 150) cohorts yield similar results, confirming that the signature is an independent risk factor for distant metastasis and outperforms anatomy-based metrics in identifying patients with high metastatic risk. Integrative analyses show that this nine-lncRNA signature correlates with immune activity and lymphocyte infiltration, which is validated by digital pathology. Our results suggest that the immune-associated nine-lncRNA signature can serve as a promising biomarker for metastasis prediction in LA-NPC.
TL;DR: In this paper , a porous organic cage is used as a high-quality support for single metal atoms by a facile stepwise nucleophilic substitution approach, and the obtained single Co atoms anchored organic cage (CoP@POC) demonstrates a prominent photocatalytic efficiency for oxidation of amines into imines in visible light.
Abstract: The construction of an appropriate support for a single atom catalyst plays an important role in delivering a high catalytic performance. However, most reported host materials suffer the drawbacks of low photostability and limited visible light absorption. Herein, we report a porous organic cage as a high-quality support for single metal atoms by a facile stepwise nucleophilic substitution approach. Thanks to its intrinsic advantages of extended visible light absorption, suppressed charge recombination, and improved electron transfer, the obtained single Co atoms anchored organic cage (CoP@POC) demonstrates a prominent photocatalytic efficiency for oxidation of amines into imines in visible light. An excellent reaction conversion and selectivity up to 99%, associated with a turnover frequency (TOF) of 1389 h–1 and 22 989 mmol g–1 h–1 are achieved based on organic cage and single Co atoms, respectively, which outperforms most reported photocatalysts. Moreover, a negligible conversion decrease in 5 repeating cycles and no photobleaching after the reaction was detected, implying a remarkable photostability of CoP@POC.
TL;DR: In this article , the use of reduced graphene oxide (rGO) for PAA activation via a non-radical pathway was explored, and the rGO-PAA system exhibited near-complete removal of typical micropollutants (MPs) within a short time (<2 min).
Abstract: Peracetic acid (PAA) serves as a potent and low-toxic oxidant for contaminant removal. Radical-mediated catalytic PAA oxidation processes are typically non-selective, rendering weakened oxidation efficacy under complex water matrices. Herein, we explored the usage of reduced graphene oxide (rGO) for PAA activation via a non-radical pathway. Outperforming the most catalytic PAA oxidation systems, the rGO-PAA system exhibits near-complete removal of typical micropollutants (MPs) within a short time (<2 min). Non-radical direct electron transfer (DET) from MPs to PAA plays a decisive role in the MP degradation, where accelerated DET is achieved by a higher potential of the rGO-PAA reactive surface complexes. Benefitting from DET, the rGO-PAA system shows robust removal of multiple MPs under complex water matrices and with low toxicity. Notably, in the DET regime, the electrostatic attraction of rGO to both PAA and target MP is a critical prerequisite for achieving efficient oxidation, depending on the conditions of solution pH and MP pKa. A heatmap model building on such an electrostatic interaction is further established as guidance for regulating the performance of the DET-mediated PAA oxidation systems. Overall, our work unveils the imperative role of DET for rGO-activated PAA oxidation, expanding the knowledge of PAA-based water treatment strategies.
TL;DR: The ESAFORM Benchmark 2021 as discussed by the authors used a 1 mm-thick, AA 6016-T4 sheet with a strong cube texture, with solid, continuum or classical shell elements and different contact models.
Abstract: This article details the ESAFORM Benchmark 2021. The deep drawing cup of a 1 mm thick, AA 6016-T4 sheet with a strong cube texture was simulated by 11 teams relying on phenomenological or crystal plasticity approaches, using commercial or self-developed Finite Element (FE) codes, with solid, continuum or classical shell elements and different contact models. The material characterization (tensile tests, biaxial tensile tests, monotonic and reverse shear tests, EBSD measurements) and the cup forming steps were performed with care (redundancy of measurements). The Benchmark organizers identified some constitutive laws but each team could perform its own identification. The methodology to reach material data is systematically described as well as the final data set. The ability of the constitutive law and of the FE model to predict Lankford and yield stress in different directions is verified. Then, the simulation results such as the earing (number and average height and amplitude), the punch force evolution and thickness in the cup wall are evaluated and analysed. The CPU time, the manpower for each step as well as the required tests versus the final prediction accuracy of more than 20 FE simulations are commented. The article aims to guide students and engineers in their choice of a constitutive law (yield locus, hardening law or plasticity approach) and data set used in the identification, without neglecting the other FE features, such as software, explicit or implicit strategy, element type and contact model.
TL;DR: In this article, molybdenum disulfide (MoS2) was first employed to enhance sulfamethoxazole (SMX) degradation in the Fe(III)/PAA process at pH 3.0.
TL;DR:
Abstract: Membrane distillation has attracted great attention in the development of sustainable desalination and zero‐discharge processes because of its possibility of recovering 100% water and the potential for integration with low‐grade heat, such as solar energy. However, the conventional membrane structures and materials afford limited flux thus obstructing its practical application. Here, ultrathin nanoporous graphene membranes are reported by selectively forming thin graphene layers on the top edges of a highly porous anodic alumina oxide support, which creates short and fast transport pathways for water vapor but not liquid. The process avoids the challenging pore‐generation and substrate‐transfer processes required to prepare regular graphene membranes. In the direct‐contact membrane distillation mode under a mild temperature pair of 65/25 °C, the nanoporous graphene membranes show an average water flux of 421.7 L m−2 h−1 with over 99.8% salt rejection, which is an order of magnitude higher than any reported polymeric membranes. The mechanism for high water flux is revealed by detailed characterizations and theoretical modeling. Outdoor field tests using water from the Red Sea heated under direct sunlight radiation show that the membranes have an average water flux of 86.3 L m−2 h−1 from 8 am to 8 pm, showing a great potential for real applications in seawater desalination.
TL;DR: The Altmetric Attention Score as mentioned in this paper is a quantitative measure of the attention that a research article has received online, and it is used to measure the importance of a paper on water treatment.
Abstract: ADVERTISEMENT RETURN TO ARTICLES ASAPPREVViewpointNEXTEmerging Challenges and Opportunities for Electrified Membranes to Enhance Water TreatmentYumeng Zhao*Yumeng ZhaoState Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, China*(Y.Z.) Phone: +86 451 86283010; email: [email protected]More by Yumeng ZhaoView Biographyhttps://orcid.org/0000-0002-9279-8501, Meng Sun*Meng SunCenter for Water and Ecology, State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing 100084, China*(M.S.) Phone: +86 10 62790565; email: [email protected]More by Meng SunView Biographyhttps://orcid.org/0000-0002-8188-9264, Lea R. WinterLea R. WinterDepartment of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520-8286, United StatesMore by Lea R. Winterhttps://orcid.org/0000-0002-6409-788X, Shihong LinShihong LinDepartment of Civil and Environmental Engineering, Vanderbilt University Nashville, Tennessee 37235, United StatesMore by Shihong Linhttps://orcid.org/0000-0001-9832-9127, Zhiwei WangZhiwei WangState Key Laboratory of Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Tongji University, Shanghai 200092, ChinaMore by Zhiwei Wanghttps://orcid.org/0000-0001-6729-2237, John C. CrittendenJohn C. CrittendenBrook Byers Institute for Sustainable Systems and School of Civil and Environmental Engineering, Georgia Institute of Technology, 828 West Peachtree Street, Atlanta, Georgia 30332, United StatesMore by John C. Crittendenhttps://orcid.org/0000-0002-9048-7208, and Jun MaJun MaState Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, ChinaMore by Jun Mahttps://orcid.org/0000-0002-0903-5547Cite this: Environ. Sci. Technol. 2022, XXXX, XXX, XXX-XXXPublication Date (Web):March 16, 2022Publication History Received21 December 2021Published online16 March 2022https://doi.org/10.1021/acs.est.1c08725© 2022 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views718Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-AlertsSUBJECTS:Separation science,Membranes,Electrical energy,Materials,Water treatment Get e-Alerts