K
Katleen De Preter
Researcher at Ghent University
Publications - 161
Citations - 24504
Katleen De Preter is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & Gene. The author has an hindex of 41, co-authored 150 publications receiving 21878 citations. Previous affiliations of Katleen De Preter include Katholieke Universiteit Leuven & Ghent University Hospital.
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Journal ArticleDOI
Cell-Free DNA as a Diagnostic and Prognostic Biomarker in Pediatric Rhabdomyosarcoma
Nathalie S.M. Lak,Lieke M. J. van Zogchel,Lily Zappeij-Kannegieter,Ahmad Javadi,Ruben Van Paemel,Charlotte Vandeputte,Katleen De Preter,Bram De Wilde,Mathieu Chicard,Yasmine Iddir,Gudrun Schleiermacher,Olivia Ruhen,Janet Shipley,Marta Fiocco,Johannes H. M. Merks,Max M. van Noesel,C. Ellen van der Schoot,Godelieve A.M. Tytgat,Janine Stutterheim +18 more
TL;DR: In this paper , the diagnostic and prognostic potential of cfDNA and ctDNA, obtained from pediatric patients with rhabdomyosarcoma, was analyzed by using droplet digital polymerase chain reaction to detect methylated RASSF1A (RASSF 1A-M).
Proceedings ArticleDOI
Abstract 5506: SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma
Bieke Decaesteker,Sara De Brouwer,Fanny De Vloed,Geertrui Denecker,Suzanne Vanhauwaert,Jolien De Wyn,Genevieve Laureys,Björn Menten,Pauline Depuydt,Patrick Reynolds,Jo Vandorpe,Kris Gevaert,Jan Koster,Sara Ek,Frank Speleman,Katleen De Preter +15 more
Journal ArticleDOI
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma
Jordan F. Hastings,Sharissa L. Latham,Alvin Kamili,Madeleine S. Wheatley,Jeremy Z. R. Han,Marie Wong-Erasmus,Monica Phimmachanh,Max Nobis,Chiara Pantarelli,Antonia L Cadell,Yolande E. I. O’Donnell,King Ho Leong,Sophie Lynn,Fan-Suo Geng,Lujing Cui,Sabrina Yan,Joanna Achinger-Kawecka,Clare Stirzaker,Murray D. Norris,Michelle Haber,Toby Trahair,Franki Speleman,Katleen De Preter,Mark J. Cowley,Ozren Bogdanovic,Paul Timpson,Thomas R. Cox,Walter Kolch,Jamie I. Fletcher,Dirk Fey,David R. Croucher +30 more
TL;DR: In this article , the influence of gene expression noise is integrated across multiple components of an apoptotic signaling network, and the memory of this initially random state is retained following chemotherapy treatment across a series of in vitro, in vivo, and patient models.
Journal ArticleDOI
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry
Bieke Decaesteker,Amber Louwagie,Siebe Loontiens,Fanny De Vloed,Sarah-Lee Bekaert,Juliette Roels,Suzanne Vanhauwaert,Sara De Brouwer,K. Sanders,Alla Berezovskaya,Geertrui Denecker,Eva D'haene,Stéphane Van Haver,Wouter Van Loocke,J. Van Dorpe,David Creytens,Nadine Van Roy,Tim Pieters,Christophe Van Neste,Matthias Fischer,Pieter Van Vlierberghe,Stephen Roberts,Johannes B. Schulte,Sara Ek,Rogier Versteeg,Jan Koster,Johan van Nes,Mark W. Zimmerman,Katleen De Preter,Franki Speleman +29 more
TL;DR: In this paper , SOX11 was identified as a dependency transcription factor in adrenergic neuroblastoma based on recurrent chromosome 2p focal gains and amplifications, specific expression in the normal sympatho-adrenal lineage and adrenergic Neuroblastoma.
Posted ContentDOI
Zipper plot: visualizing transcriptional activity of genomic regions
Francisco Avila Cobos,Jasper Anckaert,Pieter-Jan Volders,Dries Rombaut,Jo Vandesompele,Katleen De Preter,Pieter Mestdagh +6 more
TL;DR: The Zipper plot is an application that enables users to interrogate putative transcription start sites (TSSs) in relation to various features that are indicative for transcriptional activity.