K
Katleen De Preter
Researcher at Ghent University
Publications - 161
Citations - 24504
Katleen De Preter is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & Gene. The author has an hindex of 41, co-authored 150 publications receiving 21878 citations. Previous affiliations of Katleen De Preter include Katholieke Universiteit Leuven & Ghent University Hospital.
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Journal ArticleDOI
Meta-mining of copy number profiles of high-risk neuroblastoma tumors.
Pauline Depuydt,Jan Koster,Valentina Boeva,Valentina Boeva,Toby Dylan Hocking,Frank Speleman,Gudrun Schleiermacher,Gudrun Schleiermacher,Katleen De Preter +8 more
TL;DR: A unique large copy number dataset of high-risk neuroblastoma tumors is compiled, available via R2 and a Shiny web application, and the availability of patient survival data allows to further investigate the prognostic value of copy number aberrations.
Journal ArticleDOI
EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells
An De Weer,Joni Van der Meulen,Pieter Rondou,Tom Taghon,Torsten A. Konrad,Katleen De Preter,Pieter Mestdagh,Tom Van Maerken,Nadine Van Roy,Marta Jeison,Isaac Yaniv,Barbara Cauwelier,Lucien Noens,Hélène-Antoine Poirel,Peter Vandenberghe,Frédéric Lambert,Anne De Paepe,Maria Garcia Sanchez,María D. Odero,Bruno Verhasselt,Jan Philippé,J Vandesompele,Rotraud Wieser,Nicole Dastugue,Pieter Van Vlierberghe,Bruce Poppe,Frank Speleman +26 more
TL;DR: MIR449A is revealed as a crucial direct target of the MECOM locus protein EVI1 involved in the pathogenesis of MECom‐rearranged leukaemias and unravels NOTCH1 and BCL2 as important novel targets of MIR449 a.
Journal ArticleDOI
No evidence for correlation of DDX1 gene amplification with improved survival probability in patients with MYCN-amplified neuroblastomas
Katleen De Preter,Franki Speleman,Valérie Combaret,John Lunec,Julien Board,Andrew D.J. Pearson,Anne De Paepe,Nadine Van Roy,Genevieve Laureys,Jo Vandesompele +9 more
Journal ArticleDOI
High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors.
Jasmien Hoebeeck,Evi Michels,Björn Menten,Nadine Van Roy,Angelika Eggert,Alexander Schramm,Katleen De Preter,Nurten Yigit,Els De Smet,Anne De Paepe,Genevieve Laureys,Jo Vandesompele,Franki Speleman +12 more
TL;DR: The present data significantly extend previous findings and now firmly establish critical regions on 3p implicated in neuroblastoma, Interestingly, the 2 proximal regions coincide with previously defined SROs on 3 p21.3 in more frequent tumors including lung and breast cancer.
Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations
Kristof Van Schil,Sarah Naessens,Stijn Van De Sompele,Marjolein Carron,Alexander Aslanidis,Caroline Van Cauwenbergh,Anja K. Mayer,Mattias Van Heetvelde,Miriam Bauwens,Hannah Verdin,Frauke Coppieters,Michael E. Greenberg,Marty G. Yang,Marcus Karlstetter,Thomas Langmann,Katleen De Preter,Susanne Kohl,Timothy J. Cherry,Timothy J. Cherry,Bart P. Leroy,Bart P. Leroy,Elfride De Baere +21 more
TL;DR: An error in the spelling of the author Anja K. Mayer, which was incorrectly given as Anja Kathrin Mayer, has been corrected in both the PDF and HTML versions of the article as mentioned in this paper.