Katleen De Preter

TL;DR: This work employs the novel CRISPR/Cas9-based engineered DNA-binding molecule-mediated chromatin immunoprecipitation (enChIP) - mass spectrometry (MS) methodology to identify proteins that associate with the EPAS1 promoter under normoxic and hypoxic conditions and proposes a putative model where HDX negatively regulates EPAS 1 expression through a release-of-inhibition mechanism.

TL;DR: It is concluded that GD2(+)/S100A6(+) neuroblasts may represent a tumoral glial precursor subpopulation in NBT.

TL;DR: The current study identifies ERBB3 as a clear-cut marker of a GNB/GN-like expression profile, and suggests a 7-gene expression signature as a complement to histopathology analysis of neuroblastic tumours.

TL;DR: This study reports on thousands of novel RNA species across all major RNA biotypes, including a hitherto poorly-cataloged class of non-polyadenylated single-exon long non-coding RNAs.

TL;DR: The immunophenotypic landscape of primary antibody deficiencies comprises a spectrum, in which some alterations are shared between all primary antibodies deficiencies whereas others are only associated with common variable immunodeficiency.