K
Katsutoshi Kokubun
Researcher at Tokyo Dental College
Publications - 28
Citations - 3993
Katsutoshi Kokubun is an academic researcher from Tokyo Dental College. The author has contributed to research in topics: Medicine & Bone marrow. The author has an hindex of 8, co-authored 21 publications receiving 2809 citations. Previous affiliations of Katsutoshi Kokubun include Harvard University & Japanese Foundation for Cancer Research.
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Journal ArticleDOI
Biological properties of extracellular vesicles and their physiological functions
María Yáñez-Mó,Pia Siljander,Zoraida Andreu,Apolonija Bedina Zavec,Francesc E. Borràs,Edit I. Buzás,Krisztina Buzas,Krisztina Buzas,Enriqueta Casal,Francesco Cappello,Joana Carvalho,Joana Carvalho,Eva Colas,Anabela Cordeiro da Silva,Anabela Cordeiro da Silva,Stefano Fais,Juan M. Falcón-Pérez,Irene M. Ghobrial,Bernd Giebel,Mario Gimona,Mario Gimona,Michael W. Graner,Ihsan Gursel,Mayda Gursel,Niels H. H. Heegaard,Niels H. H. Heegaard,An Hendrix,Peter Kierulf,Katsutoshi Kokubun,Maja Kosanović,Veronika Kralj-Iglič,Eva-Maria Krämer-Albers,Saara Laitinen,Cecilia Lässer,Thomas Lener,Thomas Lener,Erzsébet Ligeti,Aija Linē,Georg Lipps,Alicia Llorente,Jan Lötvall,Mateja Manček-Keber,Antonio Marcilla,María Mittelbrunn,Irina Nazarenko,Esther N. M. Nolte-‘t Hoen,Tuula A. Nyman,Lorraine O'Driscoll,Mireia Olivan,Carla Oliveira,Carla Oliveira,Éva Pállinger,Hernando A. del Portillo,Hernando A. del Portillo,Jaume Reventós,Jaume Reventós,Marina Rigau,Eva Rohde,Eva Rohde,Marei Sammar,Francisco Sánchez-Madrid,Nuno Santarém,Nuno Santarém,Katharina Schallmoser,Katharina Schallmoser,Marie Stampe Ostenfeld,Willem Stoorvogel,Roman Štukelj,Susanne G. van der Grein,M. Helena Vasconcelos,M. Helena Vasconcelos,Marca H. M. Wauben,Olivier De Wever +72 more
TL;DR: A comprehensive overview of the current understanding of the physiological roles of EVs is provided, drawing on the unique EV expertise of academia-based scientists, clinicians and industry based in 27 European countries, the United States and Australia.
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Change in surface properties of zirconia and initial attachment of osteoblastlike cells with hydrophilic treatment
TL;DR: Results indicate that Blast/Etch, O2-Plasma, or UV treatment has potential in the creation and maintenance of superhydrophilic surfaces and enhancing initial attachment of osteoblast-like cells.
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Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression.
Yawara Kawano,Yawara Kawano,Oksana Zavidij,Jihye Park,Michele Moschetta,Katsutoshi Kokubun,Tarek H. Mouhieddine,Salomon Manier,Yuji Mishima,Naoka Murakami,Mark Bustoros,Romanos Sklavenitis Pistofidis,Mairead Reidy,Yu J. Shen,Mahshid Rahmat,Pavlo Lukyanchykov,Esilida Sula Karreci,Shokichi Tsukamoto,Jiantao Shi,Satoshi Takagi,Daisy Huynh,Antonio Sacco,Antonio Sacco,Yu-Tzu Tai,Marta Chesi,P. Leif Bergsagel,Aldo M. Roccaro,Aldo M. Roccaro,Jamil Azzi,Irene M. Ghobrial +29 more
TL;DR: It is demonstrated that myeloma cells drive Treg expansion and activation by secreting type 1 interferon (IFN), and blocking type 1 IFN signaling represents a potential strategy to target immunosuppressive Treg function in MM.
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Platelets Enhance Multiple Myeloma Progression via IL-1β Upregulation.
Satoshi Takagi,Shokichi Tsukamoto,Jihye Park,Kelly E. Johnson,Yawara Kawano,Michele Moschetta,Chia Jen Liu,Yuji Mishima,Katsutoshi Kokubun,Salomon Manier,Karma Salem,Daisy Huynh,Antonio Sacco,Antonio Sacco,Jodi A. Forward,Aldo M. Roccaro,Aldo M. Roccaro,Elisabeth M. Battinelli,Irene M. Ghobrial +18 more
TL;DR: RNA sequencing of platelets revealed that genes involved in platelets were enriched in patients with smoldering MM (SMM) or MM, and IL-1β is critical to platelet-mediated MM progression and might be a potential target for MM treatment.
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Motif-Programmed Artificial Extracellular Matrix
TL;DR: The creation of artificial proteins through the programming of two motifs, a natural cell attachment motif (RGD) and an artificial Ti-binding motif (minTBP-1) were found to reversibly bind Ti and to bind MC3T3-E1 osteoblast-like cells.