Author
Lee Edwards
Other affiliations: University of Manchester, University of Hertfordshire, London School of Economics and Political Science ...read more
Bio: Lee Edwards is an academic researcher from GlaxoSmithKline. The author has contributed to research in topic(s): Epithelial sodium channel & Cystic fibrosis. The author has an hindex of 25, co-authored 102 publication(s) receiving 1673 citation(s). Previous affiliations of Lee Edwards include University of Manchester & University of Hertfordshire.
Papers
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TL;DR: A broad range of synthetic photochemical transformations were optimized in both reactor modes and their yields and productivities compared and it was revealed that the productivity of flow reactors varied very little to that of their batch counterparts when the key reaction parameters were matched.
Abstract: The use of flow photochemistry and its apparent superiority over batch has been reported by a number of groups in recent years. To rigorously determine whether flow does indeed have an advantage over batch, a broad range of synthetic photochemical transformations were optimized in both reactor modes and their yields and productivities compared. Surprisingly, yields were essentially identical in all comparative cases. Even more revealing was the observation that the productivity of flow reactors varied very little to that of their batch counterparts when the key reaction parameters were matched. Those with a single layer of fluorinated ethylene propylene (FEP) had an average productivity 20% lower than that of batch, whereas three-layer reactors were 20% more productive. Finally, the utility of flow chemistry was demonstrated in the scale-up of the ring-opening reaction of a potentially explosive [1.1.1] propellane with butane-2,3-dione.
131 citations
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TL;DR: In this article, the importance of paradigmatic variety in the scholarly field of public relations is considered and the role of conflict and cooperation between different paradigms play in the development of academic fields.
Abstract: In this article I consider the importance of paradigmatic variety in the scholarly field of public relations. I reflect on the role that both conflict and cooperation between different paradigms play in the development of academic fields, and review definitions of public relations to examine the extent to which both are present in public relations scholarship. Based on this discussion, I consider the assumptions that underpin existing approaches to public relations in order to reveal the ways in which they are connected, as well as differentiated, along a series of continua. I conclude by proposing a new definition of public relations, as flow rather than organizational function, that can accommodate the range of research encompassed by these continua, thereby facilitating greater unity, inclusivity and, I would hope, dialogue in the field.
107 citations
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TL;DR: A new class of cannabinoid ligands was rationally designed from known aminoalkylindole agonists and showed good binding and functional activities at human CB1 and CB2 receptors, which led to the discovery of a novel CB1/CB2 dual agonist, naphthalen-1-yl-(4-pentyloxynaphthalanone), which displays good oral bioavailability, potent antihyperalgesic activity in animal models, and limited brain penetration.
Abstract: Selective activation of peripheral cannabinoid CB1 receptors has the potential to become a valuable therapy for chronic pain conditions as long as central nervous system effects are attenuated. A new class of cannabinoid ligands was rationally designed from known aminoalkylindole agonists and showed good binding and functional activities at human CB1 and CB2 receptors. This has led to the discovery of a novel CB1/CB2 dual agonist, naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (13), which displays good oral bioavailability, potent antihyperalgesic activity in animal models, and limited brain penetration.
88 citations
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25 Feb 2011
TL;DR: In this article, the authors discuss the implications of a socio-cultural 'turn' in public relations scholarship Lee Edwards, Manchester Business School (University of Manchester) and Caroline E. M. Hodges, Bournemouth University.
Abstract: Contributors Acknowledgements Introduction: Implications of a (radical) socio-cultural 'turn' in public relations scholarship Lee Edwards, Manchester Business School (University of Manchester) and Caroline E. M. Hodges, Bournemouth University Chapter 1. Imagining public relations anthropology Jacquie L'Etang, Stirling Media Institute Chapter 2. Public relations in the postmodern city: An ethnographic account of PR occupational culture in Mexico City Caroline E. M. Hodges, Bournemouth University Chapter 3. Public relations and storytelling Paul Elmer, University of Central Lancashire Chapter 4. Public relations and society: A Bourdieuvian perspective Lee Edwards, Manchester Business School (University of Manchester) Chapter 5. Diversity in public relations Lee Edwards, Manchester Business School (University of Manchester) Chapter 6. Communication for social transformation Caroline E. M. Hodges, Bournemouth University and Nilam McGrath, Leeds University Business School Chapter 7. Pragmatism, semiotics and sacred truth Steve Mackey, Deakin University Chapter 8. Bubble Wrap - Social Media, Public Relations, Culture and Society Kristin Demetrious, Deakin University
76 citations
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TL;DR: In this paper, the authors adopt a relational view of public relations as a profession defined by its relationships to explain the nature of power in public relations, and use Bourdieu's framework of fields, structures, habitus and capital.
Abstract: In the United Kingdom, popular sceptism about the merits of public relations has prompted self-reflection among practitioners and industry bodies. At the root of the public debate is the assumption that public relations wields unjustified social influence on behalf of already privileged organizational interests. The core concern of this discussion, therefore, is the power that a public relations has in democratic societies. This paper proposes that adopting a relational view of public relations as a profession defined by its relationships will help explicate the nature of power more effectively. Using Pierre Bourdieu's framework of fields, structures, habitus and capital, a more comprehensive picture of how power operates in public relations can be developed, which will give us a new starting point for addressing public concerns.
73 citations
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01 Apr 2000
17,060 citations
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TL;DR: In this paper, Imagined communities: Reflections on the origin and spread of nationalism are discussed. And the history of European ideas: Vol. 21, No. 5, pp. 721-722.
Abstract: (1995). Imagined communities: Reflections on the origin and spread of nationalism. History of European Ideas: Vol. 21, No. 5, pp. 721-722.
13,241 citations
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01 Jan 2015
TL;DR: Familiarity, ease of access, trust, and awareness of risks, will all be important for the future.
Abstract: 萨义德以其独特的双重身份,对西方中心权力话语做了分析,通过对文学作品、演讲演说等文本的解读,将O rie n ta lis m——"东方学",做了三重释义:一门学科、一种思维方式和一种权力话语系统,对东方学权力话语做了系统的批判,同时将东方学放入空间维度对东方学文本做了细致的解读。
3,608 citations
Book•
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01 Jan 1983
TL;DR: In this paper, the authors present a typology of nationalisms in industrial and agro-literature societies, and a discussion of the difficulties of true nationalism in industrial societies.
Abstract: Series Editor's Preface. Introduction by John Breuilly. Acknowledgements. 1. Definitions. State and nation. The nation. 2. Culture in Agrarian Society. Power and culture in the agro-literature society. The varieties of agrarian rulers. 3. Industrial Society. The society of perpetual growth. Social genetics. The age of universal high culture. 4. The Transition to an Age of Nationalism. A note on the weakness of nationalism. Wild and garden culture. 5. What is a Nation. The course of true nationalism never did run smooth. 6. Social Entropy and Equality in Industrial Society. Obstacles to entropy. Fissures and barriers. A diversity of focus. 7. A Typology of Nationalisms. The varieties of nationalist experience. Diaspora nationalism. 8. The Future of Nationalism. Industrial culture - one or many?. 9. Nationalism and Ideology. Who is for Nuremberg?. One nation, one state. 10. Conclusion. What is not being said. Summary. Select bibliography. Bilbliography of Ernest Gellner's writing: Ian Jarvie. Index
2,785 citations