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Luigi Naldini

Researcher at Vita-Salute San Raffaele University

Publications -  370
Citations -  59320

Luigi Naldini is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Genetic enhancement & Viral vector. The author has an hindex of 108, co-authored 345 publications receiving 55080 citations. Previous affiliations of Luigi Naldini include Università telematica San Raffaele & Sangamo BioSciences.

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Whole transcriptome characterization of aberrant splicing events induced by lentiviral vector integrations

Daniela Cesana, +5 more
- 01 May 2012 - 
TL;DR: It is found that SIN LV has a sharply reduced propensity to engage in aberrant splicing compared with that of vectors carrying active LTRs, and by recoding the identified vector splice sites, reduced residual read-through transcription and demonstrated an effective strategy for improving vectors.
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Role of haematopoietic cells and endothelial progenitors in tumour angiogenesis

Michele De Palma, +1 more
- 01 Aug 2006 - 
TL;DR: Bone marrow-derived cells include haematopoietic cell lineages and the recently described endothelial progenitor cells (EPCs), which are thought to directly incorporate into nascent blood vessels as bona fide endothelial cells ("building block" role).
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Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models

Andrea Casazza, +14 more
- 01 Apr 2011 - 
TL;DR: It is shown that the expression of the receptor neuropilin-1 in tumor cells is required for SEMA3A-dependent inhibition of tumor cell migration in vitro and metastatic spreading in vivo, and these data support the rationale for further investigation of SEMA2A as an anticancer molecule.
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Hepatocyte Growth Factor Is a Regulator of Monocyte-Macrophage Function

Francesco Galimi, +7 more
- 15 Jan 2001 - 
TL;DR: It is reported that HGF induces directional migration and cytokine secretion in human monocytes, and this data indicates that monocyte function is modulated by HGF in a paracrine/autocrine manner, and provide a new link between stromal environment and mononuclear phagocytes.
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Applications of gene therapy to the CNS

Ulrike Blömer, +4 more
- 01 Sep 1996 - 
TL;DR: A new lentiviral vector is focused on as a recent gene transfer method and degenerative disorders of the CNS, and their related model systems.