M. Lagos

TL;DR: People with loss-of-function mutations in the transcription factor RORC exhibit a surprising susceptibility to Mycobacterium, whereas inborn errors of interferon-γ (IFN-γ) immunity underlie mycobacterial disease.

TL;DR: Diagnostic guidelines for STAT3-deficient HIES are proposed based on a machine-learning approach to identify which features best predict a STAT3 mutation.

TL;DR: In this paper, experts from six Latin American countries met to discuss critical issues and needs in the diagnosis and management of primary immunodeficiency diseases (PIDD) in the region, and additional collaboration across countries appears feasible in at least two areas: a laboratory network to facilitate the diagnosis of PIDD, and educational programs to improve PIDD awareness.

TL;DR: Experts from six Latin American countries met to discuss critical issues and needs in the diagnosis and management of primary immunodeficiency diseases (PIDD), and additional collaboration across countries appears feasible in at least two areas: a laboratory network to facilitate the diagnosis of PIDD and educational programmes to improve PIDD awareness.