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Andrea M. Cooper

Researcher at University of Leicester

Publications -  138
Citations -  19265

Andrea M. Cooper is an academic researcher from University of Leicester. The author has contributed to research in topics: Mycobacterium tuberculosis & Immune system. The author has an hindex of 63, co-authored 136 publications receiving 17743 citations. Previous affiliations of Andrea M. Cooper include National Institutes of Health & Colorado State University.

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Journal ArticleDOI

Disseminated tuberculosis in interferon gamma gene-disrupted mice.

Andrea M. Cooper, +5 more
- 01 Dec 1993 - 
TL;DR: It is shown that mice in which the IFN-gamma gene has been disrupted were unable to contain or control a normally sublethal dose of M. tuberculosis, delivered either intravenously or aerogenically, and that despite the lack of protective immunity, some DTH-like reactivity could still be elicited.
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IL-23 and IL-17 in the establishment of protective pulmonary CD4 + T cell responses after vaccination and during Mycobacterium tuberculosis challenge

Shabaana A. Khader, +13 more
- 11 Mar 2007 - 
TL;DR: It is proposed that vaccination induces IL-17-producing CD4+ T cells that populate the lung and, after challenge, trigger the production of chemokines that recruit CD4- T cells producing interferon-γ, which ultimately restrict bacterial growth.
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Cell-Mediated Immune Responses in Tuberculosis

Andrea M. Cooper
- 20 Mar 2009 - 
TL;DR: To improve current vaccine strategies, it is necessary to understand the factors that mediate induction, expression, and regulation of the immune response in the lung and determine how to induce both known and novel immunoprotective responses without inducing immunopathologic consequences.
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Interleukin 12 (IL-12) Is Crucial to the Development of Protective Immunity in Mice Intravenously Infected with Mycobacterium tuberculosis

Andrea M. Cooper, +3 more
- 07 Jul 1997 - 
TL;DR: IL-12 is essential to the generation of a protective immune response to M. tuberculosis, with its main functions being the induction of the expression of IFN-γ and the activation of antigen-specific lymphocytes capable of creating a protective granuloma.
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Andrea Cossarizza, +462 more
- 01 Oct 2019 - 
TL;DR: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community providing the theory and key practical aspects offlow cytometry enabling immunologists to avoid the common errors that often undermine immunological data.