M
Marie-Charlotte Meinsohn
Researcher at Harvard University
Publications - 19
Citations - 481
Marie-Charlotte Meinsohn is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Liver receptor homolog-1. The author has an hindex of 8, co-authored 15 publications receiving 197 citations. Previous affiliations of Marie-Charlotte Meinsohn include Université de Montréal.
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Journal ArticleDOI
Compromised SARS-CoV-2-specific placental antibody transfer.
Caroline Atyeo,Caroline Atyeo,Krista M. Pullen,Evan A. Bordt,Stephanie Fischinger,Stephanie Fischinger,John F. Burke,Ashlin R. Michell,Matthew D. Slein,Carolin Loos,Carolin Loos,Lydia L. Shook,Adeline A. Boatin,Laura J. Yockey,David Pépin,Marie-Charlotte Meinsohn,Ngoc Minh Phuong Nguyen,Maeva Chauvin,Drucilla J. Roberts,Ilona T. Goldfarb,Juan D. Matute,Kaitlyn E. James,Lael M. Yonker,Lisa M. Bebell,Anjali J Kaimal,Kathryn J. Gray,Douglas A. Lauffenburger,Andrea G. Edlow,Galit Alter +28 more
TL;DR: Systems serology characterized the Fc-profile of influenza, pertussis, and SARS-CoV-2-specific antibodies transferred across the placenta to point to unexpected compensatory mechanisms to boost immunity in neonates, providing insights for maternal vaccine design.
Journal ArticleDOI
The Orphan Nuclear Receptors Steroidogenic Factor-1 and Liver Receptor Homolog-1: Structure, Regulation, and Essential Roles in Mammalian Reproduction
TL;DR: The NR5A orphan nuclear receptors are nonredundant factors that are crucial regulators of a panoply of biological processes, across multiple reproductive tissues.
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Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses.
Evan A. Bordt,Lydia L. Shook,Caroline Atyeo,Caroline Atyeo,Krista M. Pullen,Rose M. De Guzman,Marie-Charlotte Meinsohn,Maeva Chauvin,Stephanie Fischinger,Laura J. Yockey,Kaitlyn E. James,Rosiane Lima,Lael M. Yonker,Alessio Fasano,Sara Brigida,Lisa M. Bebell,Drucilla J. Roberts,David Pépin,Jun R Huh,Jun R Huh,Staci D. Bilbo,Staci D. Bilbo,Jonathan Z. Li,Anjali J Kaimal,Danny J. Schust,Kathryn J. Gray,Douglas A. Lauffenburger,Galit Alter,Andrea G. Edlow +28 more
TL;DR: There is a persistent bias toward higher prevalence and increased severity of coronavirus disease 2019 (COVID-19) in males as discussed by the authors, and the underlying mechanisms accounting for this sex difference remain incomplet...
Journal ArticleDOI
Genetically Defined Syngeneic Mouse Models of Ovarian Cancer as Tools for the Discovery of Combination Immunotherapy.
Sonia Iyer,Shuang Zhang,Simge Yucel,Heiko Horn,Heiko Horn,Sean G. Smith,Ferenc Reinhardt,Esmee Hoefsmit,Bimarzhan Assatova,Julia Casado,Marie-Charlotte Meinsohn,M. Inmaculada Barrasa,George W. Bell,Fernando Pérez-Villatoro,Kaisa Huhtinen,Johanna Hynninen,Jaana Oikkonen,Pamoda M. Galhenage,Shailja Pathania,Paula T. Hammond,Benjamin G. Neel,Anniina Färkkilä,Anniina Färkkilä,David Pépin,Robert A. Weinberg +24 more
TL;DR: A series of mouse models that carry genotypes of human HGSCs and grow in syngeneic immunocompetent hosts are developed to identify new immunotherapy targets in HGSC and identify follistatin as a driver of resistance to checkpoint inhibitors.
Journal ArticleDOI
Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility.
Hatice D. Saatcioglu,Motohiro Kano,Heiko Horn,Heiko Horn,LiHua Zhang,Wesley R Samore,Nicholas Nagykery,Marie-Charlotte Meinsohn,Minsuk Hyun,Rana Suliman,Joy Poulo,Joy Poulo,Jennifer Y. Hsu,Caitlin R. Sacha,Dan Wang,Guangping Gao,Kasper Lage,Kasper Lage,Esther Oliva,Mary E. Sabatini,Patricia K. Donahoe,David Pépin +21 more
TL;DR: It is reported that subluminal Misr2+ cells persist postnatally in the uterus of rodents, but recede by week 37 of gestation in humans, suggesting a progenitor function.