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Michael Hughes

Researcher at Royal Hallamshire Hospital

Publications -  615
Citations -  26328

Michael Hughes is an academic researcher from Royal Hallamshire Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 74, co-authored 531 publications receiving 24066 citations. Previous affiliations of Michael Hughes include Royal College of Physicians & St Thomas' Hospital.

Papers
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Journal ArticleDOI

Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women.

TL;DR: Improvement of quality of life (QoL) after 1 year of second-line antiretroviral therapy (ART) use in resource-limited settings (RLS) among adult men and women was similar after starting second-lines of LPV/r combined with either raltegravir or NRTIs in RLS.
Journal ArticleDOI

Use of historical marker data for assessing treatment effects in phase I/II trials when subject selection is determined by baseline marker level.

TL;DR: This work considers the scenario where data are routinely collected on a marker of disease progression on all patients attending a clinic, but the trial is restricted to patients who have a marker level within a defined range at study baseline.
Book Chapter

Non-invasive imaging of subsurface paint layers with optical coherence tomography

TL;DR: Optical coherence tomography (OCT) has been applied to the non-invasive examination of the stratigraphy of paintings and museum artefacts as discussed by the authors, which is the only technique capable of imaging noninvasively the subsurface structure of paintings.
Proceedings ArticleDOI

Electromagnetic tracking of handheld high-resolution endomicroscopy probes to assist with real-time video mosaicking

TL;DR: The proposed methodology significantly improves the quality and accuracy of reconstructed mosaics compared to reconstructions based only on conventional pair-wise image registration and can be applied to other optical biopsy techniques such as confocal endomicroscopy and endocytoscopy.