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Michael Hughes

Researcher at Royal Hallamshire Hospital

Publications -  615
Citations -  26328

Michael Hughes is an academic researcher from Royal Hallamshire Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 74, co-authored 531 publications receiving 24066 citations. Previous affiliations of Michael Hughes include Royal College of Physicians & St Thomas' Hospital.

Papers
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Journal ArticleDOI

Associations of chemokine receptor polymorphisms With HIV-1 mother-to-child transmission in sub-Saharan Africa: possible modulation of genetic effects by antiretrovirals.

Kumud K. Singh, +12 more
- 01 Nov 2008 - 
TL;DR: CCR5 promoter, CCR2, and CX3CR1 polymorphisms were associated with risk of MTCT likely through their role as an HIV-1 coreceptor or by modulating the early immune response and will need to be confirmed in validation cohorts with a large number of infected infants.
Journal Article

Evaluating surrogate markers.

Michael Hughes, +2 more
- 01 Jan 1995 - 
TL;DR: Designs in which marker evaluation is undertaken only for a random sample of subjects within a randomized trial and for all other subjects who develop a major clinical outcome will be useful in clinical trials in which a highly significant treatment difference on clinical outcome has been obtained.
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Association of diarrhoea and upper respiratory infections with weight and height gains in Bangladeshi children aged 5 to 11 years

Alberto Torres, +5 more
- 01 Jan 2000 - 
TL;DR: Diarrhoea was a significant correlate of retarded weight gain among children above preschool age, whereas upper respiratory infections were not, suggesting that increased attention should be given to the study of the continuous impact of diarrhoea in children aged over 5 years.
Journal ArticleDOI

Urinary trypsinogen activation peptides (TAP) are not increased in mild ERCP-induced pancreatitis.

Peter A. Banks, +5 more
- 01 Apr 1996 - 
TL;DR: It is concluded that measurement of urinary TAP 4 h after ERCP is not helpful in documenting mild E RCP-induced acute pancreatitis.
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Associations of proinflammatory cytokine levels with lipid profiles, growth, and body composition in HIV-infected children initiating or changing antiretroviral therapy.

Joseph S. Cervia, +8 more
- 01 Dec 2010 - 
TL;DR: In HIV-infected children initiating or changing ART, PIC were detectable at baseline and decreased over 48 weeks, and better immunologic responses were associated with greater reductions in TNF-&agr; and IL-6 and improved total/HDL cholesterol ratio.