M
Michael Hughes
Researcher at Royal Hallamshire Hospital
Publications - 615
Citations - 26328
Michael Hughes is an academic researcher from Royal Hallamshire Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 74, co-authored 531 publications receiving 24066 citations. Previous affiliations of Michael Hughes include Royal College of Physicians & St Thomas' Hospital.
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Journal ArticleDOI
A Randomized Comparison of Anthropomorphic Changes With Preferred and Alternative Efavirenz-Based Antiretroviral Regimens in Diverse Multinational Settings
Kristine M. Erlandson,Sineenart Taejaroenkul,Laura M. Smeaton,Amita Gupta,Isaac Singini,Javier R. Lama,Rosie Mngqibisa,Cynthia Firnhaber,Sandra W. Cardoso,Cecilia Kanyama,Andre L. Machado da Silva,James Hakim,Nagalingeswaran Kumarasamy,Thomas B. Campbell,Michael Hughes +14 more
TL;DR: Compared to 3TC/ZDV+EFV (N=519), participants randomized to FTC/TDF+ EFV experienced significantly greater increases in weight, mid-arm, mid thethigh, waist, and hip circumferences, and no lipoatrophy cases.
Journal ArticleDOI
Two-way mobile phone intervention compared with standard-of-care adherence support after second-line antiretroviral therapy failure: a multinational, randomised controlled trial
Robert E. Gross,Justin Ritz,Michael Hughes,Robert A. Salata,Peter Mugyenyi,Evelyn Hogg,Linda Wieclaw,Catherine Godfrey,Carole L. Wallis,John W. Mellors,Victor Mudhune,Sharlaa Badal-Faesen,Beatriz Grinsztejn,Ann C. Collier +13 more
TL;DR: Two-way MPI did not significantly improve week 48 suppression, but it did modestly affect virological failure, and people failing second-line ART might not achieve benefits from phone-based triggers or enhanced adherence support (or both).
Proceedings ArticleDOI
Autonomous scanning for endomicroscopic mosaicing and 3D fusion
TL;DR: The da Vinci® surgical robot, through the dVRK framework, is used for autonomous scanning and 2D mosaicing over a user-defined region of interest to enhance surgical procedures, by providing the operator with cellular-scale information over a larger area than could typically be achieved by manual scanning.
Journal ArticleDOI
Analysis of diagnostic error in paid malpractice claims with substandard care in a large healthcare system.
TL;DR: Although claims databases are not representative of all care delivery, their predisposition toward serious unintended injury can complement resource-intensive chart reviews and guide patient safety initiatives and suggest diagnosis-related negligent adverse events are a serious problem in the healthcare industry.
Journal ArticleDOI
Discordance between CD4 cell count and CD4 cell percentage: implications for when to start antiretroviral therapy in HIV-1 infected children.
Hiv Paediatric Prognostic Markers Collaborative Study,Katherine Boyd,David Dunn,Hannah Castro,Diana M. Gibb,Trinh Duong,Jean-Pierre Aboulker,Marc Bulterys,Mario Cortina-Borja,Clara Gabiano,Luisa Galli,Carlo Giaquinto,D. R. Harris,Michael Hughes,Ross E. McKinney,Lynne M. Mofenson,J Moye,Marie-Louise Newell,Savita Pahwa,Paul Palumbo,Christoph Rudin,Mike Sharland,William T. Shearer,Bruce Thompson,Pat A Tookey +24 more
TL;DR: In this paper, the relative prognostic value of CD4 cell count and percentage for progression to AIDS/death was investigated using time-updated Cox proportional hazards models, stratified by age.