M
Michael Hughes
Researcher at Royal Hallamshire Hospital
Publications - 615
Citations - 26328
Michael Hughes is an academic researcher from Royal Hallamshire Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 74, co-authored 531 publications receiving 24066 citations. Previous affiliations of Michael Hughes include Royal College of Physicians & St Thomas' Hospital.
Papers
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Journal ArticleDOI
Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation.
Lisard Iglesias-Carres,Michael Hughes,Cortney N. Steele,Monica A. Ponder,Kevin P. Davy,Andrew P. Neilson +5 more
TL;DR: In this paper, a review of the use of phytochemicals as TMAO-reducing agents is presented, which discusses the main mechanisms by which Trimethylamine-N-oxide (TMAO) promotes CVD, including modulation of lipid and bile acid metabolism, and the promotion of endothelial dysfunction and oxidative stress.
Journal Article
Trial design in the era of highly effective antiviral drug combinations for HIV infection.
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Does the Clinical Context Improve the Reliability of Rheumatologists Grading Digital Ulcers in Systemic Sclerosis
TL;DR: It is investigated whether clinical information from clinical contextual information in recent trials improves the reliability of rheumatologists grading DUs, and whether agreement between patients and r heumatologists is found.
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HIV-1 Protease Inhibitors and Clinical Malaria: a Secondary Analysis of the AIDS Clinical Trials Group A5208 Study
Kimberly A. Porter,Stephen R. Cole,Joseph J. Eron,Yu Zheng,Michael Hughes,Shahin Lockman,Charles Poole,Tina S. Skinner-Adams,Mina C. Hosseinipour,Doug Shaffer,Ronald D'Amico,Frederick K. Sawe,Abraham Siika,Elizabeth M. Stringer,Judith S. Currier,Tsungai Chipato,Robert A. Salata,James S. McCarthy,Steven R. Meshnick +18 more
TL;DR: The treatment with LPV/r compared to NVP had no apparent beneficial effect on the incidence of clinical malaria among HIV-infected adult women and sensitivity analyses indicated the results were robust to reasonable levels of outcome misclassification.
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Marital status, general-life satisfaction and the welfare State : A cross-national comparison
TL;DR: Mastekaasa et al. as discussed by the authors examined the relationship between general-life satisfaction and marital status cross-nationally, and found that marriage is necessary for psychological and social integration in industrialized countries.