M
Michael Hughes
Researcher at Royal Hallamshire Hospital
Publications - 615
Citations - 26328
Michael Hughes is an academic researcher from Royal Hallamshire Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 74, co-authored 531 publications receiving 24066 citations. Previous affiliations of Michael Hughes include Royal College of Physicians & St Thomas' Hospital.
Papers
More filters
Journal ArticleDOI
Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C.
Susanna Naggie,Kristen M. Marks,Michael Hughes,Daniel S. Fierer,Christine E. MacBrayne,Arthur Y. Kim,Kimberly Hollabaugh,Jhoanna Roa,Bill Symonds,Diana M. Brainard,John G. McHutchison,Marion G. Peters,Jennifer J. Kiser,Raymond T. Chung +13 more
TL;DR: Sofosbuvir-ribavirin for 12 weeks for the treatment of acute HCV genotype-1 infection in HIV-1-infected persons results in a high relapse rate.
Journal ArticleDOI
The prevalence of pain in pediatric human immunodeficiency virus/acquired immunodeficiency syndrome as reported by participants in the Pediatric Late Outcomes Study (PACTG 219).
Denise M. Gaughan,Michael Hughes,George R. Seage,George R. Seage,Peter A. Selwyn,Vincent J. Carey,Vincent J. Carey,Steven L. Gortmaker,Steven L. Gortmaker,Steven L. Gortmaker,James Oleske,James Oleske +11 more
TL;DR: Pain is a frequently encountered symptom in children and youth with HIV disease and is also associated with increased mortality, emphasizing the importance of pain management in this population.
Journal ArticleDOI
Pharmacokinetics and safety of nelfinavir when used in combination with zidovudine and lamivudine in HIV-infected pregnant women: Pediatric AIDS Clinical Trials Group (PACTG) Protocol 353.
Yvonne J. Bryson,Mark Mirochnick,Alice Stek,Lynne M. Mofenson,James D. Connor,Edmund V. Capparelli,D. H. Watts,Sharon Huang,Michael Hughes,Kathleen A. Kaiser,Lynette Purdue,Y. Asfaw,Margaret A. Keller,Elizabeth Smith +13 more
TL;DR: NFV used in combination with ZDV and 3TC was well tolerated in pregnant HIV-infected women and produced a significant improvement in HIV disease parameters.
Journal ArticleDOI
En face optical coherence tomography investigation of apical microleakage after laser-assisted endodontic treatment
Carmen Todea,Cosmin Balabuc,Cosmin Sinescu,Laura Filip,Cristina Kerezsi,Mircea Calniceanu,Meda Lavinia Negrutiu,Adrian Bradu,Michael Hughes,Adrian Gh. Podoleanu +9 more
TL;DR: En face OCT imaging proved that laser-assisted endodontic treatment improved the prognosis of root canal filling and led to a reduction in apical microleakage.
Journal ArticleDOI
Risk Factors for Opportunistic Illnesses in Children With Human Immunodeficiency Virus in the Era of Highly Active Antiretroviral Therapy
Nathalie Ylitalo,Susan B. Brogly,Michael Hughes,Sharon Nachman,Wayne M. Dankner,Russell B. Van Dyke,George R. Seage +6 more
TL;DR: Investigating the relationship between the use of highly active antiretroviral treatment (HAART) and the occurrence of opportunistic illnesses among children perinatally infected with human immunodeficiency virus found lack of a sustained response to HAART rather than age at or duration of HAART use is predictive of OI risk.