Michael Hughes

TL;DR: Raynaud’s phenomenon manifests as episodic vasospasm of the extremities in response to cold exposure, which results in pain, numbness, impaired function and reduced quality of life.

TL;DR: Time to first positive HIV- 1 DNA PCR in HIV-1-infected nonbreastfed infants (non-B HIV subtype) may differ according to maternal/infant antiretroviral regimen and may be longer with infant cART, which may have implications for scheduling infant HIV PCR-diagnostic testing and confirming final infant HIV status.

TL;DR: Three short-term antiretroviral strategies, begun simultaneously with the administration of sdNVP, resulted in a low rate of new NVP-resistance mutations when assessed at 2 and 6 weeks following completion of study treatment by standard genotype.

TL;DR: This study was undertaken to compare 2 computer‐assisted planimetry methods of measurement of digital ulcer area on photographs (ellipse and freehand regions of interest [ROIs]), and to assess the reliability of photographic calibration and the 2 methods of area measurement.

TL;DR: There was a positive correlation between vicriviroc Cmin, area under the curve, and viral load changes at week 2 in treatment-experienced HIV-infected subjects receiving no other new active antiretroviral drugs, but this correlation did not persist beyond week 16, probably because treatment response at that point also depended on having other active drugs in the regimen.