M
Michael P. Murtaugh
Researcher at University of Minnesota
Publications - 292
Citations - 14882
Michael P. Murtaugh is an academic researcher from University of Minnesota. The author has contributed to research in topics: Porcine reproductive and respiratory syndrome virus & Immune system. The author has an hindex of 59, co-authored 292 publications receiving 13744 citations. Previous affiliations of Michael P. Murtaugh include Nanjing University & South Dakota State University.
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Journal ArticleDOI
Analyses of pig genomes provide insight into porcine demography and evolution
Martien A. M. Groenen,Alan Archibald,Hirohide Uenishi,Christopher K. Tuggle,Yasuhiro Takeuchi,Max F. Rothschild,Claire Rogel-Gaillard,Chankyu Park,Denis Milan,Hendrik-Jan Megens,Shengting Li,Denis M. Larkin,Heebal Kim,Laurent A. F. Frantz,Mario Caccamo,Hyeonju Ahn,Bronwen Aken,Anna Anselmo,Christian Anthon,Loretta Auvil,Bouabid Badaoui,Craig W. Beattie,Christian Bendixen,Daniel Berman,Frank Blecha,Jonas Blomberg,Lars Bolund,Mirte Bosse,Sara Botti,Zhan Bujie,Megan Bystrom,Boris Capitanu,Denise Carvalho-Silva,Patrick Chardon,Celine Chen,Ryan Cheng,Sang-Haeng Choi,William Chow,Richard Clark,C M Clee,Richard P. M. A. Crooijmans,Harry D. Dawson,Patrice Dehais,Fioravante De Sapio,Bert Dibbits,Nizar Drou,Zhi-Qiang Du,Kellye Eversole,João Fadista,João Fadista,Susan Fairley,Thomas Faraut,Geoffrey J. Faulkner,Geoffrey J. Faulkner,Katie E. Fowler,Merete Fredholm,Eric Fritz,James G. R. Gilbert,Elisabetta Giuffra,Elisabetta Giuffra,Jan Gorodkin,Darren K. Griffin,Jennifer Harrow,Alexander Hayward,Kerstin Howe,Zhi-Liang Hu,Sean Humphray,Sean Humphray,Toby Hunt,Henrik Hornshøj,Jin-Tae Jeon,Patric Jern,Matthew Jones,Jerzy Jurka,Hiroyuki Kanamori,Ronan Kapetanovic,Jaebum Kim,Jaebum Kim,Jae-Hwan Kim,Kyu-Won Kim,Tae-Hun Kim,Greger Larson,Kyooyeol Lee,Kyung-Tai Lee,Richard M. Leggett,Harris A. Lewin,Yingrui Li,Wan Sheng Liu,Jane E. Loveland,Yao Lu,Joan K. Lunney,Jian Ma,Ole Madsen,Katherine M. Mann,Katherine M. Mann,Lucy Matthews,Stuart McLaren,Takeya Morozumi,Michael P. Murtaugh,Jitendra Narayan,Dinh Truong Nguyen,Peixiang Ni,Song-Jung Oh,Suneel Kumar Onteru,Frank Panitz,Eung-Woo Park,Hong-Seog Park,Géraldine Pascal,Yogesh Paudel,Miguel Pérez-Enciso,Ricardo H. Ramirez-Gonzalez,James M. Reecy,Sandra L. Rodriguez-Zas,Gary A. Rohrer,Lauretta A. Rund,Yongming Sang,Kyle M. Schachtschneider,Joshua G. Schraiber,John C. Schwartz,Linda Scobie,Carol Scott,Stephen M. J. Searle,Bertrand Servin,Bruce R. Southey,Göran O. Sperber,Peter F. Stadler,Jonathan V. Sweedler,Hakim Tafer,Bo Thomsen,Rashmi Wali,Jian Wang,Jun Wang,Simon D. M. White,Xun Xu,Martine Yerle,Guojie Zhang,Jianguo Zhang,Jie Zhang,Shuhong Zhao,Jane Rogers,Carol Churcher,Lawrence B. Schook +141 more
TL;DR: The assembly and analysis of the genome sequence of a female domestic Duroc pig and a comparison with the genomes of wild and domestic pigs from Europe and Asia reveal a deep phylogenetic split between European and Asian wild boars ∼1 million years ago.
Journal ArticleDOI
Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents.
TL;DR: The presence of substantial variations across the entire genome and in sgmRNA processing indicates that PRRSV has evolved independently on separate continents, and suggests that changes in swine husbandry and management may have contributed to the emergence of PRRS.
Journal ArticleDOI
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates.
Bernhard J. Hering,Martin Wijkstrom,Melanie L. Graham,Maria Hårdstedt,T Aasheim,Tun Jie,Jeffrey D. Ansite,Masahiko Nakano,Jane Cheng,Wei Li,K Moran,Uwe Christians,Colleen Finnegan,Charles D. Mills,David E.R. Sutherland,Pratima Bansal-Pakala,Michael P. Murtaugh,Nicole Kirchhof,Henk Jan Schuurman +18 more
TL;DR: It is reported that reversal of diabetes for more than 100 d in cynomolgus macaques after intraportal transplantation of cultured islets from genetically unmodified pigs without Gal-specific antibody manipulation is reported.
Journal ArticleDOI
Comparison of the structural protein coding sequences of the VR-2332 and Lelystad virus strains of the PRRS virus.
TL;DR: Hydropathy profiles indicate that the ORFs of VR-2332 and Lelystad virus correspond structurally despite significant sequence differences, consistent with the biological similarities but distinct serological properties of North American and European isolates of the virus.
Journal ArticleDOI
Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses
TL;DR: A 51 aa polypeptide was discovered that is encoded by an alternative ORF of the subgenomic mRNA encoding the major envelope glycoprotein, GP5, and which is incorporated into virions of PRRSV, suggesting that this ORF5a protein plays a significant role in arterivirology.