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Jonas Blomberg

Researcher at Uppsala University

Publications -  238
Citations -  8196

Jonas Blomberg is an academic researcher from Uppsala University. The author has contributed to research in topics: Endogenous retrovirus & Virus. The author has an hindex of 45, co-authored 238 publications receiving 7540 citations. Previous affiliations of Jonas Blomberg include Lund University & National Institutes of Health.

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Analyses of pig genomes provide insight into porcine demography and evolution

Martien A. M. Groenen, +141 more
- 15 Nov 2012 - 
TL;DR: The assembly and analysis of the genome sequence of a female domestic Duroc pig and a comparison with the genomes of wild and domestic pigs from Europe and Asia reveal a deep phylogenetic split between European and Asian wild boars ∼1 million years ago.
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Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies

TL;DR: The close relationship between disease activity in SLE patients and IFN-α serum levels suggests that activation of the type I IFN system might be of importance in the disease process.
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Classification and characterization of human endogenous retroviruses; mosaic forms are common

TL;DR: A comprehensive HERV classification and characterization approach was undertaken, which is applicable for classification of all ERVs and deduced that some noncanonical HERVs proliferated after the recombination event.
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Characterization of novel reverse transcriptase encoding human endogenous retroviral sequences similar to type A and type B retroviruses: differential transcription in normal human tissues.

TL;DR: The polymerase chain reaction was used to amplify genomic DNA and reverse-transcribed RNA from human lymphocytes, using primers derived from conserved regions within the retroviral reverse transcriptase, which revealed sequences similar to elements which cause carcinoma and are immunoregulatory in mice.
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Use of Endogenous Retroviral Sequences (ERVs) and structural markers for retroviral phylogenetic inference and taxonomy

TL;DR: Pol similarities and other structural traits contribute to a better understanding of retroviral phylogeny and are tested in a wider context than before.